PPR64_ARATH
ID PPR64_ARATH Reviewed; 1006 AA.
AC Q9SA76;
DT 01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=Pentatricopeptide repeat-containing protein At1g30610, chloroplastic;
DE AltName: Full=Protein EMBRYO DEFECTIVE 2279;
DE Flags: Precursor;
GN Name=EMB2279; OrderedLocusNames=At1g30610; ORFNames=T5I8.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY.
RX PubMed=15269332; DOI=10.1105/tpc.104.022236;
RA Lurin C., Andres C., Aubourg S., Bellaoui M., Bitton F., Bruyere C.,
RA Caboche M., Debast C., Gualberto J., Hoffmann B., Lecharny A., Le Ret M.,
RA Martin-Magniette M.-L., Mireau H., Peeters N., Renou J.-P., Szurek B.,
RA Taconnat L., Small I.;
RT "Genome-wide analysis of Arabidopsis pentatricopeptide repeat proteins
RT reveals their essential role in organelle biogenesis.";
RL Plant Cell 16:2089-2103(2004).
RN [4]
RP FUNCTION.
RX PubMed=15647901; DOI=10.1007/s00425-004-1452-x;
RA Cushing D.A., Forsthoefel N.R., Gestaut D.R., Vernon D.M.;
RT "Arabidopsis emb175 and other ppr knockout mutants reveal essential roles
RT for pentatricopeptide repeat (PPR) proteins in plant embryogenesis.";
RL Planta 221:424-436(2005).
CC -!- FUNCTION: May play a role in embryogenesis.
CC {ECO:0000269|PubMed:15647901}.
CC -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9SA76-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the PPR family. P subfamily. {ECO:0000305}.
CC -!- WEB RESOURCE: Name=Pentatricopeptide repeat proteins;
CC URL="https://ppr.plantenergy.uwa.edu.au";
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DR EMBL; AC007060; AAD25748.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE31249.1; -; Genomic_DNA.
DR PIR; D86431; D86431.
DR RefSeq; NP_174349.1; NM_102798.2. [Q9SA76-1]
DR AlphaFoldDB; Q9SA76; -.
DR SMR; Q9SA76; -.
DR STRING; 3702.AT1G30610.1; -.
DR iPTMnet; Q9SA76; -.
DR PaxDb; Q9SA76; -.
DR PRIDE; Q9SA76; -.
DR ProteomicsDB; 226397; -. [Q9SA76-1]
DR EnsemblPlants; AT1G30610.1; AT1G30610.1; AT1G30610. [Q9SA76-1]
DR GeneID; 839941; -.
DR Gramene; AT1G30610.1; AT1G30610.1; AT1G30610. [Q9SA76-1]
DR KEGG; ath:AT1G30610; -.
DR Araport; AT1G30610; -.
DR TAIR; locus:2204629; AT1G30610.
DR eggNOG; KOG4197; Eukaryota.
DR InParanoid; Q9SA76; -.
DR OrthoDB; 1344243at2759; -.
DR PhylomeDB; Q9SA76; -.
DR PRO; PR:Q9SA76; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9SA76; baseline and differential.
DR Genevisible; Q9SA76; AT.
DR GO; GO:0009507; C:chloroplast; IDA:TAIR.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0010239; P:chloroplast mRNA processing; IMP:TAIR.
DR GO; GO:0009658; P:chloroplast organization; IMP:TAIR.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR Gene3D; 1.25.40.10; -; 3.
DR InterPro; IPR044645; DG1/EMB2279-like.
DR InterPro; IPR002885; Pentatricopeptide_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR46935; PTHR46935; 1.
DR Pfam; PF01535; PPR; 2.
DR Pfam; PF13041; PPR_2; 1.
DR Pfam; PF13812; PPR_3; 1.
DR SUPFAM; SSF48452; SSF48452; 1.
DR TIGRFAMs; TIGR00756; PPR; 4.
DR PROSITE; PS51375; PPR; 10.
PE 3: Inferred from homology;
KW Alternative splicing; Chloroplast; Plastid; Reference proteome; Repeat;
KW Transit peptide.
FT TRANSIT 1..40
FT /note="Chloroplast"
FT /evidence="ECO:0000255"
FT CHAIN 41..1006
FT /note="Pentatricopeptide repeat-containing protein
FT At1g30610, chloroplastic"
FT /id="PRO_0000342805"
FT REPEAT 468..502
FT /note="PPR 1"
FT REPEAT 506..536
FT /note="PPR 2"
FT REPEAT 542..572
FT /note="PPR 3"
FT REPEAT 592..626
FT /note="PPR 4"
FT REPEAT 627..657
FT /note="PPR 5"
FT REPEAT 661..695
FT /note="PPR 6"
FT REPEAT 759..789
FT /note="PPR 7"
FT REPEAT 793..827
FT /note="PPR 8"
FT REPEAT 840..874
FT /note="PPR 9"
FT REPEAT 875..909
FT /note="PPR 10"
FT REGION 180..219
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 248..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..219
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..292
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1006 AA; 116095 MW; 339BE7E79444EF71 CRC64;
MAVTISTNAF VNASLLDESR NSFWRPLFHQ PYYNCRRVVR LNSRKLNSKV MFCLNLNTKE
VGLQKPGDKG FEFKPSFDQY LQIMESVKTA RKKKKFDRLK VEEDDGGGGN GDSVYEVKDM
KIKSGELKDE TFRKRYSRQE IVSDKRNERV FKRNGEIENH RVATDLKWSK SGESSVALKL
SKSGESSVTV PEDESFRKRY SKQEYHRSSD TSRGIERGSR GDELDLVVEE RRVQRIAKDA
RWSKSRESSV AVKWSNSGES SVTMPKDESF RRRYSKQEHH RSSDTSRGIA RGSKGDELEL
VVEERRVQRI AKDVRWSKSD ESLVPVSEDE SFRRGNPKQE MVRYQRVSDT SRGIERGSKG
DGLDLLAEER RIERLANERH EIRSSKLSGT RRIGAKRNDD DDDSLFAMET PAFRFSDESS
DIVDKPATSR VEMEDRIEKL AKVLNGADIN MPEWQFSKAI RSAKIRYTDY TVMRLIHFLG
KLGNWRRVLQ VIEWLQRQDR YKSNKIRIIY TTALNVLGKS RRPVEALNVF HAMLLQISSY
PDMVAYRSIA VTLGQAGHIK ELFYVIDTMR SPPKKKFKPT TLEKWDPRLE PDVVVYNAVL
NACVQRKQWE GAFWVLQQLK QRGQKPSPVT YGLIMEVMLA CEKYNLVHEF FRKMQKSSIP
NALAYRVLVN TLWKEGKSDE AVHTVEDMES RGIVGSAALY YDLARCLCSA GRCNEGLNMV
NFVNPVVLKL IENLIYKADL VHTIQFQLKK ICRVANKPLV VTYTGLIQAC VDSGNIKNAA
YIFDQMKKVC SPNLVTCNIM LKAYLQGGLF EEARELFQKM SEDGNHIKNS SDFESRVLPD
TYTFNTMLDT CAEQEKWDDF GYAYREMLRH GYHFNAKRHL RMVLEASRAG KEEVMEATWE
HMRRSNRIPP SPLIKERFFR KLEKGDHISA ISSLADLNGK IEETELRAFS TSAWSRVLSR
FEQDSVLRLM DDVNRRLGSR SESSDSVLGN LLSSCKDYLK TRTHNL
