ID   PPTA_ECO24              Reviewed;          75 AA.
AC   A7ZLQ4;
DT   02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Tautomerase PptA {ECO:0000255|HAMAP-Rule:MF_00718};
DE            EC=5.3.2.- {ECO:0000255|HAMAP-Rule:MF_00718};
GN   Name=pptA {ECO:0000255|HAMAP-Rule:MF_00718};
GN   OrderedLocusNames=EcE24377A_1642;
OS   Escherichia coli O139:H28 (strain E24377A / ETEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=331111;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E24377A / ETEC;
RX   PubMed=18676672; DOI=10.1128/jb.00619-08;
RA   Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F.,
RA   Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R.,
RA   Henderson I.R., Sperandio V., Ravel J.;
RT   "The pangenome structure of Escherichia coli: comparative genomic analysis
RT   of E. coli commensal and pathogenic isolates.";
RL   J. Bacteriol. 190:6881-6893(2008).
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00718}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00718}.
CC   -!- SIMILARITY: Belongs to the 4-oxalocrotonate tautomerase family. PptA
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00718}.
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DR   EMBL; CP000800; ABV20800.1; -; Genomic_DNA.
DR   RefSeq; WP_001120141.1; NC_009801.1.
DR   AlphaFoldDB; A7ZLQ4; -.
DR   SMR; A7ZLQ4; -.
DR   EnsemblBacteria; ABV20800; ABV20800; EcE24377A_1642.
DR   GeneID; 66674686; -.
DR   KEGG; ecw:EcE24377A_1642; -.
DR   HOGENOM; CLU_183611_0_1_6; -.
DR   OMA; IKCFPRD; -.
DR   Proteomes; UP000001122; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016862; F:intramolecular oxidoreductase activity, interconverting keto- and enol-groups; IEA:UniProtKB-UniRule.
DR   GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.429.10; -; 1.
DR   HAMAP; MF_00718; Tautomerase_PptA; 1.
DR   InterPro; IPR004370; 4-oxalocrotonate_tautomerase.
DR   InterPro; IPR014347; Tautomerase/MIF_sf.
DR   InterPro; IPR017284; Tautomerase_PptA.
DR   Pfam; PF01361; Tautomerase; 1.
DR   PIRSF; PIRSF037799; Tautomer_YdcE_prd; 1.
DR   SUPFAM; SSF55331; SSF55331; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Isomerase.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
FT   CHAIN           2..75
FT                   /note="Tautomerase PptA"
FT                   /id="PRO_0000348343"
FT   ACT_SITE        2
FT                   /note="Proton acceptor; via imino nitrogen"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
SQ   SEQUENCE   75 AA;  8488 MW;  94023FE556CACD0C CRC64;
     MPHIDIKCFP RELDEQQKAA LAADITDVII RHLNSKDSSI SIALQQIQPE SWQAIWDAEI
     APQMEALIKK PGYSM