ID   PPTA_ECO27              Reviewed;          75 AA.
AC   B7URK1;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   10-FEB-2009, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Tautomerase PptA {ECO:0000255|HAMAP-Rule:MF_00718};
DE            EC=5.3.2.- {ECO:0000255|HAMAP-Rule:MF_00718};
GN   Name=pptA {ECO:0000255|HAMAP-Rule:MF_00718}; OrderedLocusNames=E2348C_1598;
OS   Escherichia coli O127:H6 (strain E2348/69 / EPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=574521;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=E2348/69 / EPEC;
RX   PubMed=18952797; DOI=10.1128/jb.01238-08;
RA   Iguchi A., Thomson N.R., Ogura Y., Saunders D., Ooka T., Henderson I.R.,
RA   Harris D., Asadulghani M., Kurokawa K., Dean P., Kenny B., Quail M.A.,
RA   Thurston S., Dougan G., Hayashi T., Parkhill J., Frankel G.;
RT   "Complete genome sequence and comparative genome analysis of
RT   enteropathogenic Escherichia coli O127:H6 strain E2348/69.";
RL   J. Bacteriol. 191:347-354(2009).
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00718}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00718}.
CC   -!- SIMILARITY: Belongs to the 4-oxalocrotonate tautomerase family. PptA
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00718}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FM180568; CAS09146.1; -; Genomic_DNA.
DR   RefSeq; WP_001120147.1; NC_011601.1.
DR   AlphaFoldDB; B7URK1; -.
DR   SMR; B7URK1; -.
DR   EnsemblBacteria; CAS09146; CAS09146; E2348C_1598.
DR   KEGG; ecg:E2348C_1598; -.
DR   HOGENOM; CLU_183611_0_1_6; -.
DR   OMA; IKCFPRD; -.
DR   Proteomes; UP000008205; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016862; F:intramolecular oxidoreductase activity, interconverting keto- and enol-groups; IEA:UniProtKB-UniRule.
DR   GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.429.10; -; 1.
DR   HAMAP; MF_00718; Tautomerase_PptA; 1.
DR   InterPro; IPR004370; 4-oxalocrotonate_tautomerase.
DR   InterPro; IPR014347; Tautomerase/MIF_sf.
DR   InterPro; IPR017284; Tautomerase_PptA.
DR   Pfam; PF01361; Tautomerase; 1.
DR   PIRSF; PIRSF037799; Tautomer_YdcE_prd; 1.
DR   SUPFAM; SSF55331; SSF55331; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Isomerase.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
FT   CHAIN           2..75
FT                   /note="Tautomerase PptA"
FT                   /id="PRO_1000201579"
FT   ACT_SITE        2
FT                   /note="Proton acceptor; via imino nitrogen"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
SQ   SEQUENCE   75 AA;  8504 MW;  8DE5A18556CACD0C CRC64;
     MPHIDIKCFP RELDEQQKAA LAADITDVII RHLNSKDSSI SISLQQIQPE SWQAIWDAEI
     APQMEALIKK PGYSM