ID   PPTA_ECO57              Reviewed;          75 AA.
AC   Q8X9X8;
DT   10-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2007, sequence version 3.
DT   03-AUG-2022, entry version 106.
DE   RecName: Full=Tautomerase PptA {ECO:0000255|HAMAP-Rule:MF_00718};
DE            EC=5.3.2.- {ECO:0000255|HAMAP-Rule:MF_00718};
GN   Name=pptA {ECO:0000255|HAMAP-Rule:MF_00718};
GN   OrderedLocusNames=Z2252, ECs2064;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00718}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00718}.
CC   -!- SIMILARITY: Belongs to the 4-oxalocrotonate tautomerase family. PptA
CC       subfamily. {ECO:0000255|HAMAP-Rule:MF_00718}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAG56310.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE005174; AAG56310.1; ALT_INIT; Genomic_DNA.
DR   EMBL; BA000007; BAB35487.1; -; Genomic_DNA.
DR   PIR; B85731; B85731.
DR   PIR; H90886; H90886.
DR   RefSeq; NP_310091.1; NC_002695.1.
DR   RefSeq; WP_001120141.1; NZ_SEKU01000015.1.
DR   AlphaFoldDB; Q8X9X8; -.
DR   SMR; Q8X9X8; -.
DR   STRING; 155864.EDL933_2183; -.
DR   EnsemblBacteria; AAG56310; AAG56310; Z2252.
DR   EnsemblBacteria; BAB35487; BAB35487; ECs_2064.
DR   GeneID; 66674686; -.
DR   GeneID; 917264; -.
DR   KEGG; ece:Z2252; -.
DR   KEGG; ecs:ECs_2064; -.
DR   PATRIC; fig|386585.9.peg.2167; -.
DR   eggNOG; COG1942; Bacteria.
DR   HOGENOM; CLU_183611_0_1_6; -.
DR   OMA; IKCFPRD; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0016862; F:intramolecular oxidoreductase activity, interconverting keto- and enol-groups; IEA:UniProtKB-UniRule.
DR   GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.429.10; -; 1.
DR   HAMAP; MF_00718; Tautomerase_PptA; 1.
DR   InterPro; IPR004370; 4-oxalocrotonate_tautomerase.
DR   InterPro; IPR014347; Tautomerase/MIF_sf.
DR   InterPro; IPR017284; Tautomerase_PptA.
DR   Pfam; PF01361; Tautomerase; 1.
DR   PIRSF; PIRSF037799; Tautomer_YdcE_prd; 1.
DR   SUPFAM; SSF55331; SSF55331; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Isomerase; Reference proteome.
FT   INIT_MET        1
FT                   /note="Removed"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
FT   CHAIN           2..75
FT                   /note="Tautomerase PptA"
FT                   /id="PRO_0000209527"
FT   ACT_SITE        2
FT                   /note="Proton acceptor; via imino nitrogen"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
SQ   SEQUENCE   75 AA;  8488 MW;  94023FE556CACD0C CRC64;
     MPHIDIKCFP RELDEQQKAA LAADITDVII RHLNSKDSSI SIALQQIQPE SWQAIWDAEI
     APQMEALIKK PGYSM