PPTA_ECOHS
ID PPTA_ECOHS Reviewed; 75 AA.
AC A8A018;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Tautomerase PptA {ECO:0000255|HAMAP-Rule:MF_00718};
DE EC=5.3.2.- {ECO:0000255|HAMAP-Rule:MF_00718};
GN Name=pptA {ECO:0000255|HAMAP-Rule:MF_00718}; OrderedLocusNames=EcHS_A1545;
OS Escherichia coli O9:H4 (strain HS).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=331112;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HS;
RX PubMed=18676672; DOI=10.1128/jb.00619-08;
RA Rasko D.A., Rosovitz M.J., Myers G.S.A., Mongodin E.F., Fricke W.F.,
RA Gajer P., Crabtree J., Sebaihia M., Thomson N.R., Chaudhuri R.,
RA Henderson I.R., Sperandio V., Ravel J.;
RT "The pangenome structure of Escherichia coli: comparative genomic analysis
RT of E. coli commensal and pathogenic isolates.";
RL J. Bacteriol. 190:6881-6893(2008).
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00718}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00718}.
CC -!- SIMILARITY: Belongs to the 4-oxalocrotonate tautomerase family. PptA
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_00718}.
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DR EMBL; CP000802; ABV05872.1; -; Genomic_DNA.
DR RefSeq; WP_001120141.1; NC_009800.1.
DR AlphaFoldDB; A8A018; -.
DR SMR; A8A018; -.
DR GeneID; 66674686; -.
DR KEGG; ecx:EcHS_A1545; -.
DR HOGENOM; CLU_183611_0_1_6; -.
DR OMA; IKCFPRD; -.
DR Proteomes; UP000001123; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016862; F:intramolecular oxidoreductase activity, interconverting keto- and enol-groups; IEA:UniProtKB-UniRule.
DR GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR Gene3D; 3.30.429.10; -; 1.
DR HAMAP; MF_00718; Tautomerase_PptA; 1.
DR InterPro; IPR004370; 4-oxalocrotonate_tautomerase.
DR InterPro; IPR014347; Tautomerase/MIF_sf.
DR InterPro; IPR017284; Tautomerase_PptA.
DR Pfam; PF01361; Tautomerase; 1.
DR PIRSF; PIRSF037799; Tautomer_YdcE_prd; 1.
DR SUPFAM; SSF55331; SSF55331; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Isomerase.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
FT CHAIN 2..75
FT /note="Tautomerase PptA"
FT /id="PRO_0000348344"
FT ACT_SITE 2
FT /note="Proton acceptor; via imino nitrogen"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
SQ SEQUENCE 75 AA; 8488 MW; 94023FE556CACD0C CRC64;
MPHIDIKCFP RELDEQQKAA LAADITDVII RHLNSKDSSI SIALQQIQPE SWQAIWDAEI
APQMEALIKK PGYSM