PPTA_ECOLC
ID PPTA_ECOLC Reviewed; 75 AA.
AC B1IRZ6;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 1.
DT 25-MAY-2022, entry version 72.
DE RecName: Full=Tautomerase PptA {ECO:0000255|HAMAP-Rule:MF_00718};
DE EC=5.3.2.- {ECO:0000255|HAMAP-Rule:MF_00718};
GN Name=pptA {ECO:0000255|HAMAP-Rule:MF_00718}; OrderedLocusNames=EcolC_2195;
OS Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 /
OS WDCM 00012 / Crooks).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=481805;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks;
RA Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kiss H., Brettin T., Detter J.C., Han C.,
RA Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA Mikhailova N., Ingram L., Richardson P.;
RT "Complete sequence of Escherichia coli C str. ATCC 8739.";
RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00718}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00718}.
CC -!- SIMILARITY: Belongs to the 4-oxalocrotonate tautomerase family. PptA
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_00718}.
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DR EMBL; CP000946; ACA77834.1; -; Genomic_DNA.
DR RefSeq; WP_001120141.1; NZ_CP022959.1.
DR AlphaFoldDB; B1IRZ6; -.
DR SMR; B1IRZ6; -.
DR GeneID; 66674686; -.
DR KEGG; ecl:EcolC_2195; -.
DR HOGENOM; CLU_183611_0_1_6; -.
DR OMA; IKCFPRD; -.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016862; F:intramolecular oxidoreductase activity, interconverting keto- and enol-groups; IEA:UniProtKB-UniRule.
DR GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR Gene3D; 3.30.429.10; -; 1.
DR HAMAP; MF_00718; Tautomerase_PptA; 1.
DR InterPro; IPR004370; 4-oxalocrotonate_tautomerase.
DR InterPro; IPR014347; Tautomerase/MIF_sf.
DR InterPro; IPR017284; Tautomerase_PptA.
DR Pfam; PF01361; Tautomerase; 1.
DR PIRSF; PIRSF037799; Tautomer_YdcE_prd; 1.
DR SUPFAM; SSF55331; SSF55331; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Isomerase.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
FT CHAIN 2..75
FT /note="Tautomerase PptA"
FT /id="PRO_0000348340"
FT ACT_SITE 2
FT /note="Proton acceptor; via imino nitrogen"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
SQ SEQUENCE 75 AA; 8488 MW; 94023FE556CACD0C CRC64;
MPHIDIKCFP RELDEQQKAA LAADITDVII RHLNSKDSSI SIALQQIQPE SWQAIWDAEI
APQMEALIKK PGYSM