PPTA_ECOSM
ID PPTA_ECOSM Reviewed; 75 AA.
AC B1LFF6;
DT 02-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 29-APR-2008, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Tautomerase PptA {ECO:0000255|HAMAP-Rule:MF_00718};
DE EC=5.3.2.- {ECO:0000255|HAMAP-Rule:MF_00718};
GN Name=pptA {ECO:0000255|HAMAP-Rule:MF_00718};
GN OrderedLocusNames=EcSMS35_1713;
OS Escherichia coli (strain SMS-3-5 / SECEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=439855;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SMS-3-5 / SECEC;
RX PubMed=18708504; DOI=10.1128/jb.00661-08;
RA Fricke W.F., Wright M.S., Lindell A.H., Harkins D.M., Baker-Austin C.,
RA Ravel J., Stepanauskas R.;
RT "Insights into the environmental resistance gene pool from the genome
RT sequence of the multidrug-resistant environmental isolate Escherichia coli
RT SMS-3-5.";
RL J. Bacteriol. 190:6779-6794(2008).
CC -!- SUBUNIT: Homodimer. {ECO:0000255|HAMAP-Rule:MF_00718}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00718}.
CC -!- SIMILARITY: Belongs to the 4-oxalocrotonate tautomerase family. PptA
CC subfamily. {ECO:0000255|HAMAP-Rule:MF_00718}.
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DR EMBL; CP000970; ACB15853.1; -; Genomic_DNA.
DR RefSeq; WP_001120146.1; NC_010498.1.
DR AlphaFoldDB; B1LFF6; -.
DR SMR; B1LFF6; -.
DR EnsemblBacteria; ACB15853; ACB15853; EcSMS35_1713.
DR KEGG; ecm:EcSMS35_1713; -.
DR HOGENOM; CLU_183611_0_1_6; -.
DR OMA; IKCFPRD; -.
DR Proteomes; UP000007011; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0016862; F:intramolecular oxidoreductase activity, interconverting keto- and enol-groups; IEA:UniProtKB-UniRule.
DR GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR Gene3D; 3.30.429.10; -; 1.
DR HAMAP; MF_00718; Tautomerase_PptA; 1.
DR InterPro; IPR004370; 4-oxalocrotonate_tautomerase.
DR InterPro; IPR014347; Tautomerase/MIF_sf.
DR InterPro; IPR017284; Tautomerase_PptA.
DR Pfam; PF01361; Tautomerase; 1.
DR PIRSF; PIRSF037799; Tautomer_YdcE_prd; 1.
DR SUPFAM; SSF55331; SSF55331; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Isomerase.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
FT CHAIN 2..75
FT /note="Tautomerase PptA"
FT /id="PRO_0000348342"
FT ACT_SITE 2
FT /note="Proton acceptor; via imino nitrogen"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00718"
SQ SEQUENCE 75 AA; 8548 MW; 94093F5556CACD0C CRC64;
MPHIDIKCFP RELDEQQKAA LAADITDVII RHLNSKDSSI SIALQQIQPE SWQAIWDTEI
APQMETLIKK PGYSM