ID   PQIA_ECOL6              Reviewed;         417 AA.
AC   P0AFM0; P43670; P77566;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   20-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Intermembrane transport protein PqiA {ECO:0000250|UniProtKB:P0AFL9};
GN   Name=pqiA; OrderedLocusNames=c1086;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Component of a transport pathway that contributes to membrane
CC       integrity. {ECO:0000250|UniProtKB:P0AFL9}.
CC   -!- SUBUNIT: May form a complex composed of PqiA, PqiB and PqiC.
CC       {ECO:0000250|UniProtKB:P0AFL9}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane
CC       {ECO:0000250|UniProtKB:P0AFL9}; Multi-pass membrane protein
CC       {ECO:0000250|UniProtKB:P0AFL9}.
CC   -!- SIMILARITY: Belongs to the PqiA family. {ECO:0000305}.
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DR   EMBL; AE014075; AAN79554.1; -; Genomic_DNA.
DR   RefSeq; WP_000333176.1; NC_004431.1.
DR   AlphaFoldDB; P0AFM0; -.
DR   STRING; 199310.c1086; -.
DR   EnsemblBacteria; AAN79554; AAN79554; c1086.
DR   GeneID; 66670774; -.
DR   KEGG; ecc:c1086; -.
DR   eggNOG; COG2995; Bacteria.
DR   HOGENOM; CLU_041903_0_1_6; -.
DR   OMA; PWMMADV; -.
DR   BioCyc; ECOL199310:C1086-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR007498; PqiA-like.
DR   InterPro; IPR005219; PqiA-like_Ent.
DR   Pfam; PF04403; PqiA; 2.
DR   TIGRFAMs; TIGR00155; pqiA_fam; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..417
FT                   /note="Intermembrane transport protein PqiA"
FT                   /id="PRO_0000058555"
FT   TOPO_DOM        1..50
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFL9"
FT   TRANSMEM        51..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        72..101
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFL9"
FT   TRANSMEM        102..122
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        123..256
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFL9"
FT   TRANSMEM        257..277
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        278..284
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFL9"
FT   TRANSMEM        285..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        306..346
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFL9"
FT   TRANSMEM        347..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        368..371
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFL9"
FT   TRANSMEM        372..392
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        393..417
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000250|UniProtKB:P0AFL9"
SQ   SEQUENCE   417 AA;  46463 MW;  959FD92C83F3BC8D CRC64;
     MCEHHHAAKH ILCSQCDMLV ALPRLEHGQK AACPRCGTTL TVAWDAPRQR PTAYALAALF
     MLLLSNLFPF VNMNVAGVTS EITLLEIPGV LFSEDYASLG TFFLLFVQLV PAFCLITILL
     LVNRAELPVR LKEQLARVLF QLKTWGMAEI FLAGVLVSFV KLMAYGSIGV GSSFLPWCLF
     CVLQLRAFQC VDRRWLWDDI APMPELRQPL KPGVTGIRQG LRSCSCCTAI LPADEPVCPR
     CSTKGYVRRR NSLQWTLALL VTSIMLYLPA NILPIMVTDL LGSKMPSTIL AGVILLWSEG
     SYPVAAVIFL ASIMVPTLKM IAIAWLCWDA KGHGKRDSER MHLIYEVVEF VGRWSMIDVF
     VIAVLSALVR MGGLMSIYPA MGALMFALVV IMTMFSAMTF DPRLSWDRQP ESEHEES