ID   PQN25_CAEEL             Reviewed;         672 AA.
AC   P41951; Q95QP7;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 3.
DT   03-AUG-2022, entry version 134.
DE   RecName: Full=Prion-like-(Q/N-rich) domain-bearing protein 25;
DE   AltName: Full=Glutamine/asparagine-rich protein pqn-25;
GN   Name=pqn-25; ORFNames=D1044.3;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FO081000; CCD68371.1; -; Genomic_DNA.
DR   RefSeq; NP_741140.1; NM_171123.4.
DR   AlphaFoldDB; P41951; -.
DR   STRING; 6239.D1044.3; -.
DR   PaxDb; P41951; -.
DR   EnsemblMetazoa; D1044.3.1; D1044.3.1; WBGene00004114.
DR   GeneID; 175759; -.
DR   KEGG; cel:CELE_D1044.3; -.
DR   UCSC; D1044.3; c. elegans.
DR   CTD; 175759; -.
DR   WormBase; D1044.3; CE29743; WBGene00004114; pqn-25.
DR   eggNOG; KOG1218; Eukaryota.
DR   GeneTree; ENSGT00970000196038; -.
DR   HOGENOM; CLU_408948_0_0_1; -.
DR   InParanoid; P41951; -.
DR   OMA; CICQKNY; -.
DR   OrthoDB; 108246at2759; -.
DR   PhylomeDB; P41951; -.
DR   PRO; PR:P41951; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00004114; Expressed in larva and 5 other tissues.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   InterPro; IPR006150; Cys_repeat_1.
DR   InterPro; IPR006149; EB_dom.
DR   InterPro; IPR028150; Lustrin_cystein.
DR   Pfam; PF01683; EB; 8.
DR   Pfam; PF14625; Lustrin_cystein; 2.
DR   SMART; SM00289; WR1; 11.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..672
FT                   /note="Prion-like-(Q/N-rich) domain-bearing protein 25"
FT                   /id="PRO_0000058558"
FT   TRANSMEM        26..46
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   672 AA;  71395 MW;  1717219E5C8375A2 CRC64;
     MEETCSESPK ESNIISFIWH KLLKRVPPPI MICLFFLLLQ IFVISVVSQC PPGLTPLFSN
     SNFNQPLTCT PQDACSCYSS SGSSRFGTIC QYASTYNNYI CCYSTNTQCG SNSSPQVSAS
     GQVVTCSTNT QCASGYTCNN GACCPNTNSN TCSSNGNNGC LAGQTMVNGQ CYNSVNIGSA
     CQSTQQCLGG SQCQNNICQC YSGYVNVNQQ CVISNGLNCQ LGTVSYNSQC ITLASPGQNC
     QTSSQCIDNS VCMNQMCTCN NNYRLVYGYC VPITSSICQQ TQTLVNNQCV LLSIVGETCI
     ANQQCVGGAM CNSGTCQCTN GATAMYGYCI SSSSSSCNSN QVSINGMCYN TVQVGGSCSF
     SQQCLNNAVC TNNICVSTFC SVSCSTNQVC ISNQCYNYVS IGSQCVGSQQ CLSNSQCISS
     ICQCPQGTQQ SNGVCTGNNN NNNQCQPNQV LINNQCYNTV SIGFQCQFPQ QCLGNSQCMN
     SMCQCPTGST NVNGYCQGGS NGQCNSNQVL INNQCYNTVS IGFQCQFAQQ CLGNSQCLNS
     ICQCPSGSSN VNGYCQGGSN GQCNSNQVYY NNQCYNTVPI GSQCQITQQC LGNSQCMNSF
     CQCPSGTTNV NNFCTTSSSS SNLCSAGQTV QLDSSNQPIN CLVSTCPNNS FCQYSSSGQR
     YVCCRSTSGK KK