ID   PQQA_BRADU              Reviewed;          26 AA.
AC   Q89FG5;
DT   16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   16-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Coenzyme PQQ synthesis protein A;
DE   AltName: Full=Pyrroloquinoline quinone biosynthesis protein A;
GN   Name=pqqA; OrderedLocusNames=bsr6735;
OS   Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 /
OS   NBRC 14792 / USDA 110).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Bradyrhizobiaceae; Bradyrhizobium.
OX   NCBI_TaxID=224911;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110;
RX   PubMed=12597275; DOI=10.1093/dnares/9.6.189;
RA   Kaneko T., Nakamura Y., Sato S., Minamisawa K., Uchiumi T., Sasamoto S.,
RA   Watanabe A., Idesawa K., Iriguchi M., Kawashima K., Kohara M.,
RA   Matsumoto M., Shimpo S., Tsuruoka H., Wada T., Yamada M., Tabata S.;
RT   "Complete genomic sequence of nitrogen-fixing symbiotic bacterium
RT   Bradyrhizobium japonicum USDA110.";
RL   DNA Res. 9:189-197(2002).
CC   -!- FUNCTION: Required for coenzyme pyrroloquinoline quinone (PQQ)
CC       biosynthesis. PQQ is probably formed by cross-linking a specific
CC       glutamate to a specific tyrosine residue and excising these residues
CC       from the peptide (By similarity). {ECO:0000250}.
CC   -!- PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
CC   -!- SIMILARITY: Belongs to the PqqA family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAC52000.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; BA000040; BAC52000.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_773375.1; NC_004463.1.
DR   RefSeq; WP_007595659.1; NZ_CP011360.1.
DR   AlphaFoldDB; Q89FG5; -.
DR   STRING; 224911.27355015; -.
DR   EnsemblBacteria; BAC52000; BAC52000; BAC52000.
DR   GeneID; 66483410; -.
DR   KEGG; bja:bsr6735; -.
DR   PATRIC; fig|224911.44.peg.6756; -.
DR   eggNOG; ENOG5032A34; Bacteria.
DR   HOGENOM; CLU_219399_2_0_5; -.
DR   UniPathway; UPA00539; -.
DR   PRO; PR:Q89FG5; -.
DR   Proteomes; UP000002526; Chromosome.
DR   GO; GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00656; PQQ_syn_PqqA; 1.
DR   InterPro; IPR011725; PQQ_synth_PqqA.
DR   Pfam; PF08042; PqqA; 1.
DR   TIGRFAMs; TIGR02107; PQQ_syn_pqqA; 1.
PE   3: Inferred from homology;
KW   PQQ biosynthesis; Reference proteome.
FT   CHAIN           1..26
FT                   /note="Coenzyme PQQ synthesis protein A"
FT                   /id="PRO_0000220306"
FT   CROSSLNK        16..20
FT                   /note="Pyrroloquinoline quinone (Glu-Tyr)"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   26 AA;  2954 MW;  0DD795F85A676C70 CRC64;
     MAWKAPKIVE VPCGMEINMY VSATRK