ID   PQQA_CERS1              Reviewed;          26 AA.
AC   A3PMI6;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-APR-2007, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Coenzyme PQQ synthesis protein A {ECO:0000255|HAMAP-Rule:MF_00656};
DE   AltName: Full=Pyrroloquinoline quinone biosynthesis protein A {ECO:0000255|HAMAP-Rule:MF_00656};
GN   Name=pqqA {ECO:0000255|HAMAP-Rule:MF_00656};
GN   OrderedLocusNames=Rsph17029_2450;
OS   Cereibacter sphaeroides (strain ATCC 17029 / ATH 2.4.9) (Rhodobacter
OS   sphaeroides).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Cereibacter.
OX   NCBI_TaxID=349101;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17029 / ATH 2.4.9;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H., Pitluck S.,
RA   Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P., Schmutz J.,
RA   Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N., Richardson P.,
RA   Mackenzie C., Choudhary M., Donohue T.J., Kaplan S.;
RT   "Complete sequence of chromosome 1 of Rhodobacter sphaeroides ATCC 17029.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for coenzyme pyrroloquinoline quinone (PQQ)
CC       biosynthesis. PQQ is probably formed by cross-linking a specific
CC       glutamate to a specific tyrosine residue and excising these residues
CC       from the peptide. {ECO:0000255|HAMAP-Rule:MF_00656}.
CC   -!- PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00656}.
CC   -!- SIMILARITY: Belongs to the PqqA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00656}.
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DR   EMBL; CP000577; ABN77552.1; -; Genomic_DNA.
DR   RefSeq; WP_011841675.1; NC_009049.1.
DR   AlphaFoldDB; A3PMI6; -.
DR   EnsemblBacteria; ABN77552; ABN77552; Rsph17029_2450.
DR   GeneID; 57471121; -.
DR   KEGG; rsh:Rsph17029_2450; -.
DR   HOGENOM; CLU_219399_2_0_5; -.
DR   UniPathway; UPA00539; -.
DR   GO; GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00656; PQQ_syn_PqqA; 1.
DR   InterPro; IPR011725; PQQ_synth_PqqA.
DR   Pfam; PF08042; PqqA; 1.
DR   TIGRFAMs; TIGR02107; PQQ_syn_pqqA; 1.
PE   3: Inferred from homology;
KW   PQQ biosynthesis.
FT   CHAIN           1..26
FT                   /note="Coenzyme PQQ synthesis protein A"
FT                   /id="PRO_1000061704"
FT   CROSSLNK        16..20
FT                   /note="Pyrroloquinoline quinone (Glu-Tyr)"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00656"
SQ   SEQUENCE   26 AA;  3091 MW;  DB299B2DF6837CC2 CRC64;
     MAWKTPRYDE TPVGMEINMY ACAKRK