ID   PQQA_CUPTR              Reviewed;          24 AA.
AC   B3R8D5;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   25-MAY-2022, entry version 55.
DE   RecName: Full=Coenzyme PQQ synthesis protein A {ECO:0000255|HAMAP-Rule:MF_00656};
DE   AltName: Full=Pyrroloquinoline quinone biosynthesis protein A {ECO:0000255|HAMAP-Rule:MF_00656};
GN   Name=pqqA {ECO:0000255|HAMAP-Rule:MF_00656}; OrderedLocusNames=RALTA_B0672;
OS   Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP
OS   107171 / LMG 19424 / R1) (Ralstonia taiwanensis (strain LMG 19424)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Cupriavidus.
OX   NCBI_TaxID=977880;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 / R1;
RX   PubMed=18490699; DOI=10.1101/gr.076448.108;
RA   Amadou C., Pascal G., Mangenot S., Glew M., Bontemps C., Capela D.,
RA   Carrere S., Cruveiller S., Dossat C., Lajus A., Marchetti M., Poinsot V.,
RA   Rouy Z., Servin B., Saad M., Schenowitz C., Barbe V., Batut J., Medigue C.,
RA   Masson-Boivin C.;
RT   "Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and
RT   comparative genomics of rhizobia.";
RL   Genome Res. 18:1472-1483(2008).
CC   -!- FUNCTION: Required for coenzyme pyrroloquinoline quinone (PQQ)
CC       biosynthesis. PQQ is probably formed by cross-linking a specific
CC       glutamate to a specific tyrosine residue and excising these residues
CC       from the peptide. {ECO:0000255|HAMAP-Rule:MF_00656}.
CC   -!- PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00656}.
CC   -!- SIMILARITY: Belongs to the PqqA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00656}.
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DR   EMBL; CU633750; CAQ71291.1; -; Genomic_DNA.
DR   RefSeq; WP_012355514.1; NC_010530.1.
DR   AlphaFoldDB; B3R8D5; -.
DR   STRING; 977880.RALTA_B0672; -.
DR   EnsemblBacteria; CAQ71291; CAQ71291; RALTA_B0672.
DR   GeneID; 29765379; -.
DR   KEGG; cti:RALTA_B0672; -.
DR   HOGENOM; CLU_219131_0_0_4; -.
DR   UniPathway; UPA00539; -.
DR   Proteomes; UP000001692; Chromosome 2.
DR   GO; GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00656; PQQ_syn_PqqA; 1.
DR   InterPro; IPR011725; PQQ_synth_PqqA.
DR   Pfam; PF08042; PqqA; 1.
DR   TIGRFAMs; TIGR02107; PQQ_syn_pqqA; 1.
PE   3: Inferred from homology;
KW   PQQ biosynthesis.
FT   CHAIN           1..24
FT                   /note="Coenzyme PQQ synthesis protein A"
FT                   /id="PRO_1000131197"
FT   CROSSLNK        16..20
FT                   /note="Pyrroloquinoline quinone (Glu-Tyr)"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00656"
SQ   SEQUENCE   24 AA;  2879 MW;  2E0258621A3A6FD9 CRC64;
     MTWTTPAYTE LRLGFEITMY IANR