ID   PQQA_PSEPF              Reviewed;          24 AA.
AC   Q3K5R0;
DT   05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Coenzyme PQQ synthesis protein A {ECO:0000255|HAMAP-Rule:MF_00656};
DE   AltName: Full=Pyrroloquinoline quinone biosynthesis protein A {ECO:0000255|HAMAP-Rule:MF_00656};
GN   Name=pqqA {ECO:0000255|HAMAP-Rule:MF_00656}; OrderedLocusNames=Pfl01_5157;
OS   Pseudomonas fluorescens (strain Pf0-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=205922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Pf0-1;
RX   PubMed=19432983; DOI=10.1186/gb-2009-10-5-r51;
RA   Silby M.W., Cerdeno-Tarraga A.M., Vernikos G.S., Giddens S.R.,
RA   Jackson R.W., Preston G.M., Zhang X.-X., Moon C.D., Gehrig S.M.,
RA   Godfrey S.A.C., Knight C.G., Malone J.G., Robinson Z., Spiers A.J.,
RA   Harris S., Challis G.L., Yaxley A.M., Harris D., Seeger K., Murphy L.,
RA   Rutter S., Squares R., Quail M.A., Saunders E., Mavromatis K.,
RA   Brettin T.S., Bentley S.D., Hothersall J., Stephens E., Thomas C.M.,
RA   Parkhill J., Levy S.B., Rainey P.B., Thomson N.R.;
RT   "Genomic and genetic analyses of diversity and plant interactions of
RT   Pseudomonas fluorescens.";
RL   Genome Biol. 10:R51.1-R51.16(2009).
CC   -!- FUNCTION: Required for coenzyme pyrroloquinoline quinone (PQQ)
CC       biosynthesis. PQQ is probably formed by cross-linking a specific
CC       glutamate to a specific tyrosine residue and excising these residues
CC       from the peptide. {ECO:0000255|HAMAP-Rule:MF_00656}.
CC   -!- PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00656}.
CC   -!- SIMILARITY: Belongs to the PqqA family. {ECO:0000255|HAMAP-
CC       Rule:MF_00656}.
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DR   EMBL; CP000094; ABA76894.1; -; Genomic_DNA.
DR   RefSeq; WP_003444522.1; NC_007492.2.
DR   AlphaFoldDB; Q3K5R0; -.
DR   STRING; 205922.Pfl01_5157; -.
DR   EnsemblBacteria; ABA76894; ABA76894; Pfl01_5157.
DR   GeneID; 61878890; -.
DR   GeneID; 67382779; -.
DR   KEGG; pfo:Pfl01_5157; -.
DR   HOGENOM; CLU_219131_0_0_6; -.
DR   UniPathway; UPA00539; -.
DR   Proteomes; UP000002704; Chromosome.
DR   GO; GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00656; PQQ_syn_PqqA; 1.
DR   InterPro; IPR011725; PQQ_synth_PqqA.
DR   Pfam; PF08042; PqqA; 1.
DR   TIGRFAMs; TIGR02107; PQQ_syn_pqqA; 1.
PE   3: Inferred from homology;
KW   PQQ biosynthesis.
FT   CHAIN           1..24
FT                   /note="Coenzyme PQQ synthesis protein A"
FT                   /id="PRO_1000061702"
FT   CROSSLNK        16..20
FT                   /note="Pyrroloquinoline quinone (Glu-Tyr)"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00656"
SQ   SEQUENCE   24 AA;  2855 MW;  1813A879B7EA758F CRC64;
     MAWTKPAYTD LRIGFEVTMY FASR