PQQA_PSEU2
ID PQQA_PSEU2 Reviewed; 24 AA.
AC Q4ZMC5;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 25-MAY-2022, entry version 56.
DE RecName: Full=Coenzyme PQQ synthesis protein A {ECO:0000255|HAMAP-Rule:MF_00656};
DE AltName: Full=Pyrroloquinoline quinone biosynthesis protein A {ECO:0000255|HAMAP-Rule:MF_00656};
GN Name=pqqA {ECO:0000255|HAMAP-Rule:MF_00656}; OrderedLocusNames=Psyr_4670;
OS Pseudomonas syringae pv. syringae (strain B728a).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas; Pseudomonas syringae.
OX NCBI_TaxID=205918;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B728a;
RX PubMed=16043691; DOI=10.1073/pnas.0504930102;
RA Feil H., Feil W.S., Chain P., Larimer F., Dibartolo G., Copeland A.,
RA Lykidis A., Trong S., Nolan M., Goltsman E., Thiel J., Malfatti S.,
RA Loper J.E., Lapidus A., Detter J.C., Land M., Richardson P.M.,
RA Kyrpides N.C., Ivanova N., Lindow S.E.;
RT "Comparison of the complete genome sequences of Pseudomonas syringae pv.
RT syringae B728a and pv. tomato DC3000.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:11064-11069(2005).
CC -!- FUNCTION: Required for coenzyme pyrroloquinoline quinone (PQQ)
CC biosynthesis. PQQ is probably formed by cross-linking a specific
CC glutamate to a specific tyrosine residue and excising these residues
CC from the peptide. {ECO:0000255|HAMAP-Rule:MF_00656}.
CC -!- PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_00656}.
CC -!- SIMILARITY: Belongs to the PqqA family. {ECO:0000255|HAMAP-
CC Rule:MF_00656}.
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DR EMBL; CP000075; AAY39697.1; -; Genomic_DNA.
DR RefSeq; WP_003422658.1; NC_007005.1.
DR RefSeq; YP_237735.1; NC_007005.1.
DR AlphaFoldDB; Q4ZMC5; -.
DR STRING; 205918.Psyr_4670; -.
DR EnsemblBacteria; AAY39697; AAY39697; Psyr_4670.
DR GeneID; 61872239; -.
DR GeneID; 64463523; -.
DR GeneID; 65077326; -.
DR KEGG; psb:Psyr_4670; -.
DR eggNOG; ENOG5031JH1; Bacteria.
DR HOGENOM; CLU_219131_0_0_6; -.
DR UniPathway; UPA00539; -.
DR Proteomes; UP000000426; Chromosome.
DR GO; GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00656; PQQ_syn_PqqA; 1.
DR InterPro; IPR011725; PQQ_synth_PqqA.
DR Pfam; PF08042; PqqA; 1.
DR TIGRFAMs; TIGR02107; PQQ_syn_pqqA; 1.
PE 3: Inferred from homology;
KW PQQ biosynthesis.
FT CHAIN 1..24
FT /note="Coenzyme PQQ synthesis protein A"
FT /id="PRO_1000061703"
FT CROSSLNK 16..20
FT /note="Pyrroloquinoline quinone (Glu-Tyr)"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00656"
SQ SEQUENCE 24 AA; 2871 MW; 9A13A879B7EA6B8E CRC64;
MSWTKPAYTD LRIGFEVTMY FASR