ID   PQQB_KLEPN              Reviewed;         308 AA.
AC   P27504;
DT   01-AUG-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1992, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Coenzyme PQQ synthesis protein B;
DE   AltName: Full=Pyrroloquinoline quinone biosynthesis protein B;
GN   Name=pqqB;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 15380 / DSM 2026 / NCTC 418 / NCIMB 418;
RX   PubMed=1313537; DOI=10.1007/bf00280008;
RA   Meulenberg J.J.M., Sellink E., Riegman N.H., Postma P.W.;
RT   "Nucleotide sequence and structure of the Klebsiella pneumoniae pqq
RT   operon.";
RL   Mol. Gen. Genet. 232:284-294(1992).
RN   [2]
RP   FUNCTION.
RC   STRAIN=ATCC 15380 / DSM 2026 / NCTC 418 / NCIMB 418;
RX   PubMed=7665488; DOI=10.1128/jb.177.17.5088-5098.1995;
RA   Velterop J.S., Sellink E., Meulenberg J.J., David S., Bulder I.,
RA   Postma P.W.;
RT   "Synthesis of pyrroloquinoline quinone in vivo and in vitro and detection
RT   of an intermediate in the biosynthetic pathway.";
RL   J. Bacteriol. 177:5088-5098(1995).
CC   -!- FUNCTION: May be involved in the transport of PQQ or its precursor to
CC       the periplasm. {ECO:0000269|PubMed:7665488}.
CC   -!- PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
CC   -!- SIMILARITY: Belongs to the PqqB family. {ECO:0000305}.
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DR   EMBL; X58778; CAA41580.1; -; Genomic_DNA.
DR   PIR; S20454; S20454.
DR   RefSeq; WP_004225004.1; NZ_UGLG01000003.1.
DR   AlphaFoldDB; P27504; -.
DR   SMR; P27504; -.
DR   UniPathway; UPA00539; -.
DR   GO; GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd16274; PQQB-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00653; PQQ_syn_PqqB; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR011842; PQQ_synth_PqqB.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
DR   TIGRFAMs; TIGR02108; PQQ_syn_pqqB; 1.
PE   3: Inferred from homology;
KW   PQQ biosynthesis; Transport.
FT   CHAIN           1..308
FT                   /note="Coenzyme PQQ synthesis protein B"
FT                   /id="PRO_0000219999"
SQ   SEQUENCE   308 AA;  33464 MW;  0819C69D68A271D6 CRC64;
     MFIKVLGSAA GGGFPQWNCN CANCQGLRDG TIQAAPRTQS SIIVSDNGKE WVLCNASPDI
     SQQIAHTPEL NKAGVLRGTH IGGIILTDSQ IDHTTGLLSL REGCPHQVWC TPEVHEDLST
     GFPVFTMLRH WNGGLVHHPI APQQPFTVDA CPDLQFTAVP IASNAPPYSP YRDRPLPGHN
     VALFIENRRN GQTLFYAPGL GEPDETLLPW LQKADCLLID GTVWQDDELQ AAGVGRNTGR
     DMGHLALGDE HGMMALLASL PAKRKILIHI NNTNPILNKQ SPQRQALTQQ GIEVSWDGMA
     ITLQDTAC