ID   PQQB_METCA              Reviewed;         304 AA.
AC   Q608P3;
DT   15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Coenzyme PQQ synthesis protein B;
DE   AltName: Full=Pyrroloquinoline quinone biosynthesis protein B;
GN   Name=pqqB; OrderedLocusNames=MCA1446;
OS   Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Methylococcales;
OC   Methylococcaceae; Methylococcus.
OX   NCBI_TaxID=243233;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 33009 / NCIMB 11132 / Bath;
RX   PubMed=15383840; DOI=10.1371/journal.pbio.0020303;
RA   Ward N.L., Larsen O., Sakwa J., Bruseth L., Khouri H.M., Durkin A.S.,
RA   Dimitrov G., Jiang L., Scanlan D., Kang K.H., Lewis M.R., Nelson K.E.,
RA   Methe B.A., Wu M., Heidelberg J.F., Paulsen I.T., Fouts D.E., Ravel J.,
RA   Tettelin H., Ren Q., Read T.D., DeBoy R.T., Seshadri R., Salzberg S.L.,
RA   Jensen H.B., Birkeland N.K., Nelson W.C., Dodson R.J., Grindhaug S.H.,
RA   Holt I.E., Eidhammer I., Jonasen I., Vanaken S., Utterback T.R.,
RA   Feldblyum T.V., Fraser C.M., Lillehaug J.R., Eisen J.A.;
RT   "Genomic insights into methanotrophy: the complete genome sequence of
RT   Methylococcus capsulatus (Bath).";
RL   PLoS Biol. 2:1616-1628(2004).
CC   -!- FUNCTION: May be involved in the transport of PQQ or its precursor to
CC       the periplasm, in association with PQQ biosynthesis, but is not
CC       absolutely required for this synthesis.
CC   -!- PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
CC   -!- SIMILARITY: Belongs to the PqqB family. {ECO:0000305}.
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DR   EMBL; AE017282; AAU92561.1; -; Genomic_DNA.
DR   RefSeq; WP_010960723.1; NC_002977.6.
DR   AlphaFoldDB; Q608P3; -.
DR   SMR; Q608P3; -.
DR   STRING; 243233.MCA1446; -.
DR   PRIDE; Q608P3; -.
DR   EnsemblBacteria; AAU92561; AAU92561; MCA1446.
DR   KEGG; mca:MCA1446; -.
DR   eggNOG; COG1235; Bacteria.
DR   HOGENOM; CLU_061120_0_0_6; -.
DR   OMA; FYIPGCA; -.
DR   OrthoDB; 1712770at2; -.
DR   UniPathway; UPA00539; -.
DR   Proteomes; UP000006821; Chromosome.
DR   GO; GO:0018189; P:pyrroloquinoline quinone biosynthetic process; ISS:JCVI.
DR   CDD; cd16274; PQQB-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00653; PQQ_syn_PqqB; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR011842; PQQ_synth_PqqB.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
DR   TIGRFAMs; TIGR02108; PQQ_syn_pqqB; 1.
PE   3: Inferred from homology;
KW   PQQ biosynthesis; Reference proteome; Transport.
FT   CHAIN           1..304
FT                   /note="Coenzyme PQQ synthesis protein B"
FT                   /id="PRO_0000220000"
SQ   SEQUENCE   304 AA;  33584 MW;  D4A0687C63723E27 CRC64;
     MIIRVLGAGA GGGFPQWNCR CDNCRRFREK NINARGRTQS SIAVSADGQR WVLFNASPDI
     RSQLEAFPAS HPSKGVRDTG IHAIVLIDSQ IDHTTGLLML RESTRPLQVY CSEMVKQDLS
     TGFPLFRMLE HYCGVEQHTV PLDGSGFTIP GIEGLKFSTH SLKSKAPPYS PHRHDPHEGD
     NIGVIVENLE NGRKLYYAPG LGEIEPHVRA AMEAADCLLV DGTFWREDEM RHAGICDKLA
     REMGHLPQSG PGGMLEILNT LPNARKVLIH INNTNPILDE DSPQYRTLSE AGVEVAYDGL
     EIVL