ID   PQQB_METEP              Reviewed;         299 AA.
AC   A9W3R2;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Coenzyme PQQ synthesis protein B {ECO:0000255|HAMAP-Rule:MF_00653};
DE   AltName: Full=Pyrroloquinoline quinone biosynthesis protein B {ECO:0000255|HAMAP-Rule:MF_00653};
GN   Name=pqqB {ECO:0000255|HAMAP-Rule:MF_00653}; OrderedLocusNames=Mext_1819;
OS   Methylorubrum extorquens (strain PA1) (Methylobacterium extorquens).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylorubrum.
OX   NCBI_TaxID=419610;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PA1;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Pitluck S., Saunders E., Brettin T., Bruce D., Detter J.C.,
RA   Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E.,
RA   Marx C., Richardson P.;
RT   "Complete sequence of Methylobacterium extorquens PA1.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in the transport of PQQ or its precursor to
CC       the periplasm. {ECO:0000255|HAMAP-Rule:MF_00653}.
CC   -!- PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00653}.
CC   -!- SIMILARITY: Belongs to the PqqB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00653}.
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DR   EMBL; CP000908; ABY30218.1; -; Genomic_DNA.
DR   RefSeq; WP_012253379.1; NC_010172.1.
DR   AlphaFoldDB; A9W3R2; -.
DR   SMR; A9W3R2; -.
DR   STRING; 419610.Mext_1819; -.
DR   EnsemblBacteria; ABY30218; ABY30218; Mext_1819.
DR   KEGG; mex:Mext_1819; -.
DR   eggNOG; COG1235; Bacteria.
DR   HOGENOM; CLU_061120_0_0_5; -.
DR   OMA; FYIPGCA; -.
DR   BioCyc; MEXT419610:MEXT_RS09215-MON; -.
DR   UniPathway; UPA00539; -.
DR   GO; GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd16274; PQQB-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00653; PQQ_syn_PqqB; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR011842; PQQ_synth_PqqB.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
DR   TIGRFAMs; TIGR02108; PQQ_syn_pqqB; 1.
PE   3: Inferred from homology;
KW   PQQ biosynthesis; Transport.
FT   CHAIN           1..299
FT                   /note="Coenzyme PQQ synthesis protein B"
FT                   /id="PRO_1000131163"
SQ   SEQUENCE   299 AA;  32089 MW;  F3DD3CF3EC014E0D CRC64;
     MHVVILGSAA GGGVPQWNCR CSICSLAWAG DSRVRPRTQS SIAVSPDGER WLLLNASPDI
     RQQIQANPQM HPREGLRHSP IHAVLLTNGD VDHVAGLLTL REGQPFTLYA TPGILASVSD
     NRVFDVMAAE VVKRQTIALN ETFEPVPGLS VTLFSVPGKV PLWLEDASME IGAETETTVG
     TMIEAGGKRL AYIPGCARVT EDLKARIAGA DALLFDGTVL EDDDMIRAGV GTKTGWRMGH
     IQMNGETGSI ASLADVEIGR RVFVHINNTN PVLIEDSSER ASVEARGWTV AHDGLTLDL