ID   PQQB_METFL              Reviewed;         305 AA.
AC   Q50437;
DT   16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Coenzyme PQQ synthesis protein B {ECO:0000255|HAMAP-Rule:MF_00653};
DE   AltName: Full=Coenzyme PQQ synthesis protein D;
DE   AltName: Full=Pyrroloquinoline quinone biosynthesis protein B {ECO:0000255|HAMAP-Rule:MF_00653};
GN   Name=pqqB {ECO:0000255|HAMAP-Rule:MF_00653}; Synonyms=pqqD;
OS   Methylobacillus flagellatus.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Nitrosomonadales;
OC   Methylophilaceae; Methylobacillus.
OX   NCBI_TaxID=405;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8768519; DOI=10.1111/j.1574-6968.1996.tb08380.x;
RA   Gomelsky M., Biville F., Gasser F., Tsygankov Y.D.;
RT   "Identification and characterization of the pqqDGC gene cluster involved in
RT   pyrroloquinoline quinone production in an obligate methylotroph
RT   Methylobacillus flagellatum.";
RL   FEMS Microbiol. Lett. 141:169-176(1996).
CC   -!- FUNCTION: May be involved in the transport of PQQ or its precursor to
CC       the periplasm.
CC   -!- PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00653}.
CC   -!- SIMILARITY: Belongs to the PqqB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00653}.
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DR   EMBL; L78064; AAB42380.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q50437; -.
DR   SMR; Q50437; -.
DR   UniPathway; UPA00539; -.
DR   GO; GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd16274; PQQB-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00653; PQQ_syn_PqqB; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR011842; PQQ_synth_PqqB.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
DR   TIGRFAMs; TIGR02108; PQQ_syn_pqqB; 1.
PE   3: Inferred from homology;
KW   PQQ biosynthesis; Transport.
FT   CHAIN           1..305
FT                   /note="Coenzyme PQQ synthesis protein B"
FT                   /id="PRO_0000220002"
SQ   SEQUENCE   305 AA;  33432 MW;  127B09BBC1738975 CRC64;
     MHIHVLGSAA GGGFPQWNCN CPNCDGLRKG TIKAKKRTQS SICVSADGIN WVLFNTSPDI
     LQQIQEFAPL QPGRAIRDTG VVGIVLIDAQ IDHTTGLLML REGQVKREIY CTDMVYQDLT
     TGNPLLNILD HYCGVNRHDI PIDGKHSFSV EHAPGLRFTA VALKSAAPPY SPHRHDPHPG
     DTIGVLIEDL NNGKKAFYAP GLGEIEPHLP ALMEQADCIM VDGTFWTDTE MLDMGLMSKK
     ARDIGHNPQS GPGGMMEVLD GYPGARRVLI HINNTNPILR EDSAERVELT RRGIEVAYDG
     MDIIL