ID   PQQB_PSEAE              Reviewed;         304 AA.
AC   Q9I2C3; Q9ZA99;
DT   16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Coenzyme PQQ synthesis protein B {ECO:0000255|HAMAP-Rule:MF_00653};
DE   AltName: Full=Pyrroloquinoline quinone biosynthesis protein B {ECO:0000255|HAMAP-Rule:MF_00653};
GN   Name=pqqB {ECO:0000255|HAMAP-Rule:MF_00653}; OrderedLocusNames=PA1986;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-52.
RC   STRAIN=ATCC 17933;
RX   PubMed=10075429; DOI=10.1099/13500872-145-2-471;
RA   Schobert M., Goerisch H.;
RT   "Cytochrome c550 is an essential component of the quinoprotein ethanol
RT   oxidation system in Pseudomonas aeruginosa: cloning and sequencing of the
RT   genes encoding cytochrome c550 and an adjacent acetaldehyde
RT   dehydrogenase.";
RL   Microbiology 145:471-481(1999).
CC   -!- FUNCTION: May be involved in the transport of PQQ or its precursor to
CC       the periplasm. {ECO:0000255|HAMAP-Rule:MF_00653}.
CC   -!- PATHWAY: Cofactor biosynthesis; pyrroloquinoline quinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_00653}.
CC   -!- SIMILARITY: Belongs to the PqqB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00653}.
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DR   EMBL; AE004091; AAG05374.1; -; Genomic_DNA.
DR   EMBL; AF068264; AAC79661.1; -; Genomic_DNA.
DR   PIR; B83397; B83397.
DR   RefSeq; NP_250676.1; NC_002516.2.
DR   RefSeq; WP_003113495.1; NZ_QZGE01000026.1.
DR   AlphaFoldDB; Q9I2C3; -.
DR   SMR; Q9I2C3; -.
DR   STRING; 287.DR97_5861; -.
DR   PaxDb; Q9I2C3; -.
DR   PRIDE; Q9I2C3; -.
DR   DNASU; 880354; -.
DR   EnsemblBacteria; AAG05374; AAG05374; PA1986.
DR   GeneID; 880354; -.
DR   KEGG; pae:PA1986; -.
DR   PATRIC; fig|208964.12.peg.2070; -.
DR   PseudoCAP; PA1986; -.
DR   HOGENOM; CLU_061120_0_0_6; -.
DR   InParanoid; Q9I2C3; -.
DR   OMA; FYIPGCA; -.
DR   PhylomeDB; Q9I2C3; -.
DR   BioCyc; PAER208964:G1FZ6-2024-MON; -.
DR   UniPathway; UPA00539; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0018189; P:pyrroloquinoline quinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   CDD; cd16274; PQQB-like_MBL-fold; 1.
DR   Gene3D; 3.60.15.10; -; 1.
DR   HAMAP; MF_00653; PQQ_syn_PqqB; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR011842; PQQ_synth_PqqB.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SUPFAM; SSF56281; SSF56281; 1.
DR   TIGRFAMs; TIGR02108; PQQ_syn_pqqB; 1.
PE   3: Inferred from homology;
KW   PQQ biosynthesis; Reference proteome; Transport.
FT   CHAIN           1..304
FT                   /note="Coenzyme PQQ synthesis protein B"
FT                   /id="PRO_0000220003"
SQ   SEQUENCE   304 AA;  33019 MW;  71CC0744F8D799E0 CRC64;
     MHIRILGSAA GGGFPQWNCN CRNCRGVRDG SVAAQPRTQS SIALSDDGER WILCNASPDI
     RAQIAAFPAL QPARRPRDTA IGAIVLLDSQ IDHTTGLLSL REGCPHEVWC TQMVHQDLSE
     GFPLFPMLSH WNGGLRHRPI ALDGEPFAIP ACPRLRFTAI PLRSSAPPYS PHRGDPHPGD
     NIGLFVEDLD SAGALFYAPG LGEVDEALLE WMRRADCLLV DGTLWRDDEM LVCEVGDKLG
     RQMGHLAQSG PGGMLEVLAK VPAARKVLIH INNTNPILDT ASAERAELDA SGIEVAWDGM
     HIQL