ID   ATG12_MEDTR             Reviewed;          95 AA.
AC   Q1SF86;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Ubiquitin-like protein ATG12;
DE   AltName: Full=Autophagy-related protein 12;
DE            Short=APG12-like;
GN   Name=ATG12; Synonyms=APG12;
OS   Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX   NCBI_TaxID=3880;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   The international Medicago genome annotation group;
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Ubiquitin-like protein involved in cytoplasm to vacuole
CC       transport (Cvt) and autophagy vesicles formation. Conjugation with ATG5
CC       through a ubiquitin-like conjugating system is essential for its
CC       function. ATG12/ATG5 conjugate has an essential role in plant nutrient
CC       recycling (By similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ATG12 family. {ECO:0000305}.
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DR   EMBL; AC144645; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_003627265.1; XM_003627217.2.
DR   AlphaFoldDB; Q1SF86; -.
DR   SMR; Q1SF86; -.
DR   STRING; 3880.AET01741; -.
DR   EnsemblPlants; AET01741; AET01741; MTR_8g020500.
DR   GeneID; 11423981; -.
DR   Gramene; AET01741; AET01741; MTR_8g020500.
DR   eggNOG; KOG3439; Eukaryota.
DR   HOGENOM; CLU_106795_3_1_1; -.
DR   OMA; LFIYVHQ; -.
DR   ExpressionAtlas; Q1SF86; differential.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000045; P:autophagosome assembly; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR007242; Atg12.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR13385; PTHR13385; 1.
DR   Pfam; PF04110; APG12; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
PE   3: Inferred from homology;
KW   Autophagy; Cytoplasm; Isopeptide bond; Protein transport; Transport;
KW   Ubl conjugation pathway.
FT   CHAIN           1..95
FT                   /note="Ubiquitin-like protein ATG12"
FT                   /id="PRO_0000287216"
FT   CROSSLNK        95
FT                   /note="Glycyl lysine isopeptide (Gly-Lys) (interchain with
FT                   K-? in ATG5)"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   95 AA;  10593 MW;  3C401AC9B0BD1845 CRC64;
     MAAAESPTSV RKVVVHLRAT GDAPILKQSK FKIAGTDKFA KVIDFLRRQL HRESLFVYVN
     SAFSPNPDEL VIDLYNNFGF DGKLVVNYAC SMAWG