PR10_CAVPO
ID PR10_CAVPO Reviewed; 92 AA.
AC P20658;
DT 01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1991, sequence version 1.
DT 25-MAY-2022, entry version 75.
DE RecName: Full=Protein 10;
DE AltName: Full=29 kDa brain-specific calcium-binding protein;
DE Flags: Fragments;
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141;
RN [1]
RP PROTEIN SEQUENCE.
RC TISSUE=Brain;
RX PubMed=2602362; DOI=10.1073/pnas.86.24.10139;
RA Winsky L., Nakata H., Martin B.M., Jacobowitz D.M.;
RT "Isolation, partial amino acid sequence, and immunohistochemical
RT localization of a brain-specific calcium-binding protein.";
RL Proc. Natl. Acad. Sci. U.S.A. 86:10139-10143(1989).
CC -!- TISSUE SPECIFICITY: Brain.
CC -!- MISCELLANEOUS: Binds calcium.
CC -!- SIMILARITY: Belongs to the calbindin family. {ECO:0000305}.
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DR PIR; A34520; A34520.
DR AlphaFoldDB; P20658; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR InterPro; IPR029646; CALB2.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR PANTHER; PTHR19972:SF4; PTHR19972:SF4; 2.
DR SUPFAM; SSF47473; SSF47473; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 1: Evidence at protein level;
KW Calcium; Direct protein sequencing; Reference proteome.
FT CHAIN <1..>92
FT /note="Protein 10"
FT /id="PRO_0000073482"
FT DOMAIN 18..29
FT /note="EF-hand"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT NON_CONS 17..18
FT /evidence="ECO:0000305"
FT NON_CONS 27..28
FT /evidence="ECO:0000305"
FT NON_CONS 41..42
FT /evidence="ECO:0000305"
FT NON_CONS 76..77
FT /evidence="ECO:0000305"
FT NON_CONS 82..83
FT /evidence="ECO:0000305"
FT NON_TER 1
FT NON_TER 92
SQ SEQUENCE 92 AA; 11067 MW; D1CCD66C148A7F6A CRC64;
EIWKHFDADE NGYIEGKFMQ KYDKNSDQHV GSSAEFMEAW RDMSRLLPVQ ENFLLKFQGM
KLTSEEFNAI FTFYDKNEPA ILEMNIQQLW NY