PR15L_HUMAN
ID PR15L_HUMAN Reviewed; 103 AA.
AC Q9BU68; D3DTU0;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 123.
DE RecName: Full=Proline-rich protein 15-like protein;
DE AltName: Full=Protein ATAD4;
GN Name=PRR15L; Synonyms=ATAD4;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Lung;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the PRR15 family. {ECO:0000305}.
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DR EMBL; CH471109; EAW94779.1; -; Genomic_DNA.
DR EMBL; CH471109; EAW94780.1; -; Genomic_DNA.
DR EMBL; BC002865; AAH02865.1; -; mRNA.
DR CCDS; CCDS11523.1; -.
DR RefSeq; NP_077296.1; NM_024320.3.
DR RefSeq; XP_005257720.1; XM_005257663.4.
DR RefSeq; XP_005257721.1; XM_005257664.2.
DR RefSeq; XP_005257722.1; XM_005257665.1.
DR RefSeq; XP_005257723.1; XM_005257666.4.
DR AlphaFoldDB; Q9BU68; -.
DR BioGRID; 122587; 1.
DR STRING; 9606.ENSP00000300557; -.
DR iPTMnet; Q9BU68; -.
DR PhosphoSitePlus; Q9BU68; -.
DR BioMuta; PRR15L; -.
DR EPD; Q9BU68; -.
DR MassIVE; Q9BU68; -.
DR MaxQB; Q9BU68; -.
DR PaxDb; Q9BU68; -.
DR PeptideAtlas; Q9BU68; -.
DR PRIDE; Q9BU68; -.
DR ProteomicsDB; 79057; -.
DR Antibodypedia; 17807; 75 antibodies from 17 providers.
DR DNASU; 79170; -.
DR Ensembl; ENST00000300557.3; ENSP00000300557.2; ENSG00000167183.3.
DR GeneID; 79170; -.
DR KEGG; hsa:79170; -.
DR MANE-Select; ENST00000300557.3; ENSP00000300557.2; NM_024320.4; NP_077296.1.
DR UCSC; uc002imp.5; human.
DR CTD; 79170; -.
DR DisGeNET; 79170; -.
DR GeneCards; PRR15L; -.
DR HGNC; HGNC:28149; PRR15L.
DR HPA; ENSG00000167183; Tissue enhanced (intestine, pancreas, stomach).
DR neXtProt; NX_Q9BU68; -.
DR OpenTargets; ENSG00000167183; -.
DR PharmGKB; PA165432527; -.
DR VEuPathDB; HostDB:ENSG00000167183; -.
DR eggNOG; ENOG502S3QC; Eukaryota.
DR GeneTree; ENSGT00940000154534; -.
DR HOGENOM; CLU_144251_0_0_1; -.
DR InParanoid; Q9BU68; -.
DR OMA; ADSSWWK; -.
DR OrthoDB; 1542535at2759; -.
DR PhylomeDB; Q9BU68; -.
DR TreeFam; TF333189; -.
DR PathwayCommons; Q9BU68; -.
DR BioGRID-ORCS; 79170; 13 hits in 1058 CRISPR screens.
DR GenomeRNAi; 79170; -.
DR Pharos; Q9BU68; Tdark.
DR PRO; PR:Q9BU68; -.
DR Proteomes; UP000005640; Chromosome 17.
DR RNAct; Q9BU68; protein.
DR Bgee; ENSG00000167183; Expressed in ileal mucosa and 128 other tissues.
DR ExpressionAtlas; Q9BU68; baseline and differential.
DR Genevisible; Q9BU68; HS.
DR InterPro; IPR028237; PRR15.
DR PANTHER; PTHR14581; PTHR14581; 1.
DR Pfam; PF15321; ATAD4; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..103
FT /note="Proline-rich protein 15-like protein"
FT /id="PRO_0000294352"
FT REGION 28..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..103
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 103 AA; 11705 MW; 073C897D479709B9 CRC64;
MTTEIGWWKL TFLRKKKSTP KVLYEIPDTY AQTEGDAEPP RPDAGGPNSD FNTRLEKIVD
KSTKGKHVKV SNSGRFKEKK KVRATLAENP NLFDDHEEGR SSK