PR15L_MOUSE
ID PR15L_MOUSE Reviewed; 100 AA.
AC Q8JZM2; Q8C307;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2002, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Proline-rich protein 15-like protein;
DE AltName: Full=Protein ATAD4;
GN Name=Prr15l; Synonyms=Atad4;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Ovary, Oviduct, and Uterus;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Colon, and Salivary gland;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Kidney, Lung, and Pancreas;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
CC -!- SIMILARITY: Belongs to the PRR15 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAC39930.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR EMBL; AK077279; BAC36726.1; -; mRNA.
DR EMBL; AK087566; BAC39930.1; ALT_SEQ; mRNA.
DR EMBL; AL596384; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC022765; AAH22765.1; -; mRNA.
DR EMBL; BC024510; AAH24510.1; -; mRNA.
DR EMBL; BC034192; AAH34192.1; -; mRNA.
DR EMBL; BC034213; AAH34213.1; -; mRNA.
DR EMBL; BC036171; AAH36171.1; -; mRNA.
DR CCDS; CCDS25307.1; -.
DR RefSeq; NP_666138.1; NM_146026.1.
DR RefSeq; XP_006533083.1; XM_006533020.3.
DR RefSeq; XP_006533084.1; XM_006533021.3.
DR RefSeq; XP_006533085.1; XM_006533022.3.
DR RefSeq; XP_011247239.1; XM_011248937.2.
DR AlphaFoldDB; Q8JZM2; -.
DR STRING; 10090.ENSMUSP00000103262; -.
DR iPTMnet; Q8JZM2; -.
DR PhosphoSitePlus; Q8JZM2; -.
DR MaxQB; Q8JZM2; -.
DR PaxDb; Q8JZM2; -.
DR PeptideAtlas; Q8JZM2; -.
DR PRIDE; Q8JZM2; -.
DR ProteomicsDB; 291648; -.
DR Antibodypedia; 17807; 75 antibodies from 17 providers.
DR DNASU; 217138; -.
DR Ensembl; ENSMUST00000054311; ENSMUSP00000056614; ENSMUSG00000047040.
DR Ensembl; ENSMUST00000062172; ENSMUSP00000056647; ENSMUSG00000047040.
DR Ensembl; ENSMUST00000107633; ENSMUSP00000103259; ENSMUSG00000047040.
DR Ensembl; ENSMUST00000107636; ENSMUSP00000103262; ENSMUSG00000047040.
DR GeneID; 217138; -.
DR KEGG; mmu:217138; -.
DR UCSC; uc007lcy.1; mouse.
DR CTD; 79170; -.
DR MGI; MGI:2387599; Prr15l.
DR VEuPathDB; HostDB:ENSMUSG00000047040; -.
DR eggNOG; ENOG502S3QC; Eukaryota.
DR GeneTree; ENSGT00940000154534; -.
DR HOGENOM; CLU_144251_0_0_1; -.
DR InParanoid; Q8JZM2; -.
DR OMA; NPEMFPG; -.
DR OrthoDB; 1542535at2759; -.
DR PhylomeDB; Q8JZM2; -.
DR TreeFam; TF333189; -.
DR BioGRID-ORCS; 217138; 3 hits in 73 CRISPR screens.
DR ChiTaRS; Prr15l; mouse.
DR PRO; PR:Q8JZM2; -.
DR Proteomes; UP000000589; Chromosome 11.
DR RNAct; Q8JZM2; protein.
DR Bgee; ENSMUSG00000047040; Expressed in right kidney and 98 other tissues.
DR Genevisible; Q8JZM2; MM.
DR InterPro; IPR028237; PRR15.
DR PANTHER; PTHR14581; PTHR14581; 1.
DR Pfam; PF15321; ATAD4; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..100
FT /note="Proline-rich protein 15-like protein"
FT /id="PRO_0000294353"
FT REGION 29..51
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 100 AA; 11359 MW; 92335F091133919A CRC64;
MTEVGWWKLT FLRKKKSTPK VLYEIPDTYA QTEGGAEPPG PDAGDPHSDF NSRLEKIVDK
NTKGKHVKVS NSGRFKEKKK VRAMLAENPN LFDDRENKGQ