PR1B3_ARATH
ID PR1B3_ARATH Reviewed; 217 AA.
AC Q9FLB6; Q8W042;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=PRA1 family protein B3;
DE Short=AtPRA1.B3;
DE AltName: Full=Prenylated Rab acceptor 2;
GN Name=PRA1B3; Synonyms=PRA2; OrderedLocusNames=At5g05380;
GN ORFNames=K18I23.19;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RA Pay A., Nagy F., Merkle T.;
RT "Isolation and characterization of members of a new protein family from
RT Arabidopsis thaliana that specifically interact with prenylated Rab
RT proteins and SNAREs.";
RL Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT features of the regions of 1,381,565 bp covered by twenty one physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:131-145(1998).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INTERACTION WITH PRA1B1; PRA1B2;
RP PRA1B4; PRA1B5; PRA1B6 AND PRA1E, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18583532; DOI=10.1104/pp.108.122226;
RA Alvim Kamei C.L., Boruc J., Vandepoele K., Van den Daele H., Maes S.,
RA Russinova E., Inze D., de Veylder L.;
RT "The PRA1 gene family in Arabidopsis.";
RL Plant Physiol. 147:1735-1749(2008).
CC -!- FUNCTION: May be involved in both secretory and endocytic intracellular
CC trafficking in the endosomal/prevacuolar compartments. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with PRA1B1, PRA1B2, PRA1B4, PRA1B5, PRA1B6 and
CC PRA1E. {ECO:0000269|PubMed:18583532}.
CC -!- SUBCELLULAR LOCATION: Endosome membrane {ECO:0000269|PubMed:18583532};
CC Multi-pass membrane protein {ECO:0000269|PubMed:18583532}.
CC -!- TISSUE SPECIFICITY: Expressed in hypocotyls and shoot apex.
CC {ECO:0000269|PubMed:18583532}.
CC -!- SIMILARITY: Belongs to the PRA1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAC80645.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AJ249727; CAC80645.1; ALT_INIT; mRNA.
DR EMBL; AB010692; BAB09981.1; -; Genomic_DNA.
DR EMBL; CP002688; AED90867.1; -; Genomic_DNA.
DR EMBL; AK175650; BAD43413.1; -; mRNA.
DR EMBL; AK176498; BAD44261.1; -; mRNA.
DR EMBL; AK176635; BAD44398.1; -; mRNA.
DR EMBL; BT025281; ABF19034.1; -; mRNA.
DR RefSeq; NP_001318484.1; NM_001342816.1.
DR AlphaFoldDB; Q9FLB6; -.
DR STRING; 3702.AT5G05380.1; -.
DR PaxDb; Q9FLB6; -.
DR PRIDE; Q9FLB6; -.
DR ProteomicsDB; 226411; -.
DR EnsemblPlants; AT5G05380.1; AT5G05380.1; AT5G05380.
DR GeneID; 830420; -.
DR Gramene; AT5G05380.1; AT5G05380.1; AT5G05380.
DR KEGG; ath:AT5G05380; -.
DR Araport; AT5G05380; -.
DR TAIR; locus:2153589; AT5G05380.
DR eggNOG; KOG3142; Eukaryota.
DR HOGENOM; CLU_060198_1_0_1; -.
DR InParanoid; Q9FLB6; -.
DR PhylomeDB; Q9FLB6; -.
DR PRO; PR:Q9FLB6; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FLB6; baseline and differential.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IDA:TAIR.
DR InterPro; IPR004895; Prenylated_rab_accept_PRA1.
DR PANTHER; PTHR19317; PTHR19317; 1.
DR Pfam; PF03208; PRA1; 1.
PE 1: Evidence at protein level;
KW Endosome; Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..217
FT /note="PRA1 family protein B3"
FT /id="PRO_0000352252"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 98..118
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 138..158
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 162..182
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 193..213
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 217 AA; 23529 MW; 2A7BF9CA35DD7369 CRC64;
MMANPPTLPI SDHSGGGSQS QQPVSTPAFR TFLSRLSSSI RQSLSQRRPW LELVDRSAIS
RPESLTDAYS RIRRNLPYFK VNYVTIVSLV LALSLLSHPF SLLVLLCLFC AWIFLYLFRP
SDQPLVVLGR TFSDRETLGV LVILTIVVVF LTSVGSLLTS ALMIGFGIVC LHGAFRVPED
LFLDDQEPAN TGLLSFLSGA ATSAAVAAAS TPASGRV
