ID   PR1B_TOBAC              Reviewed;         168 AA.
AC   P07053;
DT   01-APR-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1988, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Pathogenesis-related protein 1B;
DE            Short=PR-1B;
DE   Flags: Precursor;
OS   Nicotiana tabacum (Common tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Samsun NN; TISSUE=Leaf;
RX   PubMed=2308824; DOI=10.1093/nar/18.1.181;
RA   Ohshima M., Harada N., Matsuoka M., Ohashi Y.;
RT   "The nucleotide sequence of pathogenesis-related (PR) 1b protein gene of
RT   tobacco.";
RL   Nucleic Acids Res. 18:181-181(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=cv. Samsun NN;
RX   PubMed=16453665; DOI=10.1002/j.1460-2075.1986.tb04174.x;
RA   Cornelissen B.J.C., Hooft van Huijsduijnen R.A.M., van Loon L.C., Bol J.F.;
RT   "Molecular characterization of messenger RNAs for 'pathogenesis-related'
RT   proteins 1a, 1b and 1c, induced by TMV infection of tobacco.";
RL   EMBO J. 5:37-40(1986).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [MRNA] OF 16-168.
RC   STRAIN=cv. Xanthi;
RX   PubMed=3186451; DOI=10.1093/nar/16.20.9861;
RA   Cutt J.R., Dixon D.D., Carr J.P., Klessig D.F.;
RT   "Isolation and nucleotide sequence of cDNA clones for the pathogenesis-
RT   related proteins PR1a, PR1b and PR1c of Nicotiana tabacum cv. Xanthi nc
RT   induced by TMV infection.";
RL   Nucleic Acids Res. 16:9861-9861(1988).
RN   [4]
RP   SUBCELLULAR LOCATION.
RX   PubMed=2026137; DOI=10.1002/j.1460-2075.1991.tb07650.x;
RA   Dixon D.C., Cutt J.R., Klessig D.F.;
RT   "Differential targeting of the tobacco PR-1 pathogenesis-related proteins
RT   to the extracellular space and vacuoles of crystal idioblasts.";
RL   EMBO J. 10:1317-1324(1991).
CC   -!- FUNCTION: Probably involved in the defense reaction of plants against
CC       pathogens.
CC   -!- SUBCELLULAR LOCATION: Vacuole {ECO:0000269|PubMed:2026137}.
CC       Note=Accumulates in within the vacuoles of specialized cells known as
CC       crystal idioblasts.
CC   -!- INDUCTION: Synthesized during pathogen infection or other stress-
CC       related responses.
CC   -!- PTM: Three disulfide bonds are present. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CRISP family. {ECO:0000305}.
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DR   EMBL; D90197; BAA14221.1; -; mRNA.
DR   EMBL; X03465; CAA27183.1; -; mRNA.
DR   EMBL; X12486; CAA31009.1; -; mRNA.
DR   EMBL; X17680; CAA35665.1; -; Genomic_DNA.
DR   PIR; A25006; A25006.
DR   PIR; B24620; B24620.
DR   AlphaFoldDB; P07053; -.
DR   SMR; P07053; -.
DR   Proteomes; UP000084051; Unplaced.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
DR   GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR   GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.33.10; -; 1.
DR   InterPro; IPR018244; Allrgn_V5/Tpx1_CS.
DR   InterPro; IPR014044; CAP_domain.
DR   InterPro; IPR035940; CAP_sf.
DR   InterPro; IPR001283; CRISP-related.
DR   PANTHER; PTHR10334; PTHR10334; 1.
DR   Pfam; PF00188; CAP; 1.
DR   PRINTS; PR00837; V5TPXLIKE.
DR   SMART; SM00198; SCP; 1.
DR   SUPFAM; SSF55797; SSF55797; 1.
DR   PROSITE; PS01009; CRISP_1; 1.
DR   PROSITE; PS01010; CRISP_2; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Pathogenesis-related protein; Plant defense;
KW   Reference proteome; Signal; Vacuole.
FT   SIGNAL          1..30
FT   CHAIN           31..168
FT                   /note="Pathogenesis-related protein 1B"
FT                   /id="PRO_0000006301"
FT   DOMAIN          38..156
FT                   /note="SCP"
FT   CONFLICT        16
FT                   /note="S -> A (in Ref. 3; CAA31009)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   168 AA;  18500 MW;  61FCE3B87A7F31F1 CRC64;
     MGFFLFSQMP SFFLVSTLLL FLIISHSSHA QNSQQDYLDA HNTARADVGV EPLTWDNGVA
     AYAQNYVSQL AADCNLVHSH GQYGENLAQG SGDFMTAAKA VEMWVDEKQY YDHDSNTCAQ
     GQVCGHYTQV VWRNSVRVGC ARVKCNNGGY VVSCNYDPPG NVIGQSPY