PR1F1_ARATH
ID PR1F1_ARATH Reviewed; 180 AA.
AC Q9FZ63;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 25-MAY-2022, entry version 99.
DE RecName: Full=PRA1 family protein F1;
DE Short=AtPRA1.F1;
GN Name=PRA1F1; OrderedLocusNames=At1g17700; ORFNames=F11A6.4;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R.F., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INTERACTION WITH PRA1F2, GENE
RP FAMILY, AND NOMENCLATURE.
RX PubMed=18583532; DOI=10.1104/pp.108.122226;
RA Alvim Kamei C.L., Boruc J., Vandepoele K., Van den Daele H., Maes S.,
RA Russinova E., Inze D., de Veylder L.;
RT "The PRA1 gene family in Arabidopsis.";
RL Plant Physiol. 147:1735-1749(2008).
CC -!- FUNCTION: May be involved in both secretory and endocytic intracellular
CC trafficking in the endosomal/prevacuolar compartments. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with PRA1F2. {ECO:0000269|PubMed:18583532}.
CC -!- SUBCELLULAR LOCATION: Endosome membrane {ECO:0000269|PubMed:18583532};
CC Multi-pass membrane protein {ECO:0000269|PubMed:18583532}.
CC -!- TISSUE SPECIFICITY: Expressed in hypocotyls, leaf bases and shoot apex.
CC {ECO:0000269|PubMed:18583532}.
CC -!- SIMILARITY: Belongs to the PRA1 family. {ECO:0000305}.
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DR EMBL; AC034257; AAF99811.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE29623.1; -; Genomic_DNA.
DR EMBL; BT012593; AAT06412.1; -; mRNA.
DR EMBL; BT014815; AAT41798.1; -; mRNA.
DR PIR; H86311; H86311.
DR RefSeq; NP_173212.1; NM_101632.4.
DR AlphaFoldDB; Q9FZ63; -.
DR IntAct; Q9FZ63; 1.
DR STRING; 3702.AT1G17700.1; -.
DR iPTMnet; Q9FZ63; -.
DR PaxDb; Q9FZ63; -.
DR PRIDE; Q9FZ63; -.
DR ProteomicsDB; 226413; -.
DR EnsemblPlants; AT1G17700.1; AT1G17700.1; AT1G17700.
DR GeneID; 838346; -.
DR Gramene; AT1G17700.1; AT1G17700.1; AT1G17700.
DR KEGG; ath:AT1G17700; -.
DR Araport; AT1G17700; -.
DR TAIR; locus:2007948; AT1G17700.
DR eggNOG; KOG3142; Eukaryota.
DR HOGENOM; CLU_060198_2_1_1; -.
DR OMA; TRTNNQH; -.
DR OrthoDB; 1344798at2759; -.
DR PhylomeDB; Q9FZ63; -.
DR PRO; PR:Q9FZ63; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FZ63; baseline and differential.
DR Genevisible; Q9FZ63; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IDA:TAIR.
DR InterPro; IPR004895; Prenylated_rab_accept_PRA1.
DR PANTHER; PTHR19317; PTHR19317; 1.
DR Pfam; PF03208; PRA1; 1.
PE 1: Evidence at protein level;
KW Endosome; Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..180
FT /note="PRA1 family protein F1"
FT /id="PRO_0000352259"
FT TRANSMEM 63..83
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 180 AA; 20445 MW; 73CFA48D0CA04B1A CRC64;
MTTYGTNQKS SNDLAPKLEY ITRGINQHKR SGLATRRPWK QMLDLGSFNF PRKLATVITR
IRANTVYFQT NYTIVVLFSV FLSLIWNPFS LLVLLALLGA WLFLYFLRDE PLTVFDREID
HRIVLIIMSV ITLSILFLTD AKLNIAVAIV AGALAVLSHA AVRKTEDLFQ TDEETSLLNP
