PR1F2_ARATH
ID PR1F2_ARATH Reviewed; 189 AA.
AC Q9C889;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 105.
DE RecName: Full=PRA1 family protein F2 {ECO:0000303|PubMed:18583532};
DE Short=AtPRA1.F2 {ECO:0000303|PubMed:18583532};
DE AltName: Full=Prenylated Rab acceptor 7 {ECO:0000303|PubMed:18845362};
GN Name=PRA1F2 {ECO:0000303|PubMed:18583532};
GN Synonyms=PRA7 {ECO:0000303|PubMed:18845362};
GN OrderedLocusNames=At1g55190 {ECO:0000312|Araport:AT1G55190};
GN ORFNames=F7A10.20 {ECO:0000312|EMBL:AAG51564.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY, AND SUBCELLULAR LOCATION [LARGE SCALE
RP ANALYSIS].
RX PubMed=17151019; DOI=10.1074/mcp.m600250-mcp200;
RA Jaquinod M., Villiers F., Kieffer-Jaquinod S., Hugouvieux V., Bruley C.,
RA Garin J., Bourguignon J.;
RT "A proteomics dissection of Arabidopsis thaliana vacuoles isolated from
RT cell culture.";
RL Mol. Cell. Proteomics 6:394-412(2007).
RN [6]
RP SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INTERACTION WITH PRA1D; PRA1F3
RP AND PRA1F1, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18583532; DOI=10.1104/pp.108.122226;
RA Alvim Kamei C.L., Boruc J., Vandepoele K., Van den Daele H., Maes S.,
RA Russinova E., Inze D., de Veylder L.;
RT "The PRA1 gene family in Arabidopsis.";
RL Plant Physiol. 147:1735-1749(2008).
RN [7]
RP INTERACTION WITH ACD11 AND BPA1, AND DISRUPTION PHENOTYPE.
RX PubMed=18845362; DOI=10.1016/j.jplph.2008.08.003;
RA Petersen N.H., Joensen J., McKinney L.V., Brodersen P., Petersen M.,
RA Hofius D., Mundy J.;
RT "Identification of proteins interacting with Arabidopsis ACD11.";
RL J. Plant Physiol. 166:661-666(2009).
CC -!- FUNCTION: May be involved in both secretory and endocytic intracellular
CC trafficking in the endosomal/prevacuolar compartments. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with PRA1F1, PRA1F3 and PRA1D. Interacts with ACD11
CC and BPA1 (PubMed:18845362). {ECO:0000269|PubMed:18583532,
CC ECO:0000269|PubMed:18845362}.
CC -!- INTERACTION:
CC Q9C889; Q8LA96: At4g17720; NbExp=3; IntAct=EBI-2010949, EBI-4425250;
CC -!- SUBCELLULAR LOCATION: Endosome membrane {ECO:0000269|PubMed:18583532};
CC Multi-pass membrane protein {ECO:0000269|PubMed:18583532}. Vacuole
CC membrane {ECO:0000269|PubMed:17151019}; Multi-pass membrane protein
CC {ECO:0000255}.
CC -!- TISSUE SPECIFICITY: Expressed in hypocotyls and trichomes.
CC {ECO:0000269|PubMed:18583532}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000305|PubMed:18845362}.
CC -!- SIMILARITY: Belongs to the PRA1 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC027034; AAG51564.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33200.1; -; Genomic_DNA.
DR EMBL; BT004089; AAO42116.1; -; mRNA.
DR EMBL; BT005098; AAO50631.1; -; mRNA.
DR EMBL; AY086167; AAM63371.1; -; mRNA.
DR PIR; F96593; F96593.
DR RefSeq; NP_564679.1; NM_104392.2.
DR AlphaFoldDB; Q9C889; -.
DR BioGRID; 27187; 24.
DR IntAct; Q9C889; 25.
DR STRING; 3702.AT1G55190.1; -.
DR PaxDb; Q9C889; -.
DR PRIDE; Q9C889; -.
DR ProteomicsDB; 226317; -.
DR EnsemblPlants; AT1G55190.1; AT1G55190.1; AT1G55190.
DR GeneID; 841962; -.
DR Gramene; AT1G55190.1; AT1G55190.1; AT1G55190.
DR KEGG; ath:AT1G55190; -.
DR Araport; AT1G55190; -.
DR TAIR; locus:2035701; AT1G55190.
DR eggNOG; KOG3142; Eukaryota.
DR HOGENOM; CLU_060198_2_1_1; -.
DR InParanoid; Q9C889; -.
DR OMA; TRRPWKI; -.
DR OrthoDB; 1344798at2759; -.
DR PhylomeDB; Q9C889; -.
DR PRO; PR:Q9C889; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C889; differential.
DR Genevisible; Q9C889; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016192; P:vesicle-mediated transport; IDA:TAIR.
DR InterPro; IPR004895; Prenylated_rab_accept_PRA1.
DR PANTHER; PTHR19317; PTHR19317; 1.
DR Pfam; PF03208; PRA1; 1.
PE 1: Evidence at protein level;
KW Endosome; Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport; Vacuole.
FT CHAIN 1..189
FT /note="PRA1 family protein F2"
FT /id="PRO_0000352260"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 145..162
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 189 AA; 21072 MW; 5CD0E6FDC629B430 CRC64;
MTNYGAIPTS SHPSPAIDLE YISRAKHRIK SGLATRRPWK SMFDFESMTL PHGFFDAISR
IKTNLGYFRA NYAIGVLFIL FLSLLYHPTS LIVLSILVVF WIFLYFLRDE PLVVFGYQID
DRTVLIGLSV LTVVMLLLTH ATSNILGSLL TAAVLVLIHA AVRRSDNLFL DEEAAAVTEA
SGLMSYPSS
