PR1F3_ARATH
ID PR1F3_ARATH Reviewed; 188 AA.
AC Q9LIC6; Q8L959;
DT 14-OCT-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=PRA1 family protein F3 {ECO:0000303|PubMed:18583532};
DE Short=AtPRA1.F3 {ECO:0000303|PubMed:18583532};
DE AltName: Full=Prenylated Rab acceptor 8 {ECO:0000303|PubMed:18845362};
GN Name=PRA1F3 {ECO:0000303|PubMed:18583532};
GN Synonyms=PRA8 {ECO:0000303|PubMed:18845362};
GN OrderedLocusNames=At3g13720 {ECO:0000312|Araport:AT3G13720};
GN ORFNames=MMM17.14 {ECO:0000312|EMBL:BAB01921.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INTERACTION WITH PRA1F2 AND
RP PRA1D, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18583532; DOI=10.1104/pp.108.122226;
RA Alvim Kamei C.L., Boruc J., Vandepoele K., Van den Daele H., Maes S.,
RA Russinova E., Inze D., de Veylder L.;
RT "The PRA1 gene family in Arabidopsis.";
RL Plant Physiol. 147:1735-1749(2008).
RN [6]
RP INTERACTION WITH ACD11 AND BPA1, SUBCELLULAR LOCATION, AND DISRUPTION
RP PHENOTYPE.
RX PubMed=18845362; DOI=10.1016/j.jplph.2008.08.003;
RA Petersen N.H., Joensen J., McKinney L.V., Brodersen P., Petersen M.,
RA Hofius D., Mundy J.;
RT "Identification of proteins interacting with Arabidopsis ACD11.";
RL J. Plant Physiol. 166:661-666(2009).
CC -!- FUNCTION: May be involved in both secretory and endocytic intracellular
CC trafficking in the endosomal/prevacuolar compartments. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with PRA1F2 and PRA1D (PubMed:18583532). Interacts
CC with ACD11 and BPA1 (PubMed:18845362). {ECO:0000269|PubMed:18583532,
CC ECO:0000269|PubMed:18845362}.
CC -!- INTERACTION:
CC Q9LIC6; Q9M354: AGD6; NbExp=3; IntAct=EBI-2010961, EBI-21138098;
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000305|PubMed:18583532}; Multi-pass membrane protein
CC {ECO:0000305|PubMed:18583532}. Membrane {ECO:0000269|PubMed:18845362};
CC Multi-pass membrane protein {ECO:0000255}. Cytoplasm
CC {ECO:0000269|PubMed:18845362}.
CC -!- TISSUE SPECIFICITY: Expressed in lateral roots, lateral root caps and
CC columella cells. {ECO:0000269|PubMed:18583532}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype.
CC {ECO:0000305|PubMed:18845362}.
CC -!- SIMILARITY: Belongs to the PRA1 family. {ECO:0000305}.
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DR EMBL; AP001307; BAB01921.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE75403.1; -; Genomic_DNA.
DR EMBL; BT004174; AAO42194.1; -; mRNA.
DR EMBL; BT004952; AAO50485.1; -; mRNA.
DR EMBL; AY088623; AAM66945.1; -; mRNA.
DR RefSeq; NP_566461.1; NM_112222.4.
DR AlphaFoldDB; Q9LIC6; -.
DR BioGRID; 5915; 49.
DR IntAct; Q9LIC6; 42.
DR STRING; 3702.AT3G13720.1; -.
DR PaxDb; Q9LIC6; -.
DR PRIDE; Q9LIC6; -.
DR ProteomicsDB; 225981; -.
DR EnsemblPlants; AT3G13720.1; AT3G13720.1; AT3G13720.
DR GeneID; 820581; -.
DR Gramene; AT3G13720.1; AT3G13720.1; AT3G13720.
DR KEGG; ath:AT3G13720; -.
DR Araport; AT3G13720; -.
DR TAIR; locus:2091556; AT3G13720.
DR eggNOG; KOG3142; Eukaryota.
DR HOGENOM; CLU_060198_2_1_1; -.
DR InParanoid; Q9LIC6; -.
DR OMA; DRWYAPV; -.
DR OrthoDB; 1344798at2759; -.
DR PhylomeDB; Q9LIC6; -.
DR PRO; PR:Q9LIC6; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LIC6; baseline and differential.
DR Genevisible; Q9LIC6; AT.
DR GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0016192; P:vesicle-mediated transport; IDA:TAIR.
DR InterPro; IPR004895; Prenylated_rab_accept_PRA1.
DR PANTHER; PTHR19317; PTHR19317; 1.
DR Pfam; PF03208; PRA1; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Endoplasmic reticulum; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..188
FT /note="PRA1 family protein F3"
FT /id="PRO_0000352261"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 95..115
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 145..165
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 160
FT /note="S -> A (in Ref. 4; AAM66945)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 188 AA; 21116 MW; FA3ECEC01E3CC94D CRC64;
MTNYGAIPTS SHASPLVDVE SLSRAKHRIK AGLATRRAWR VMFDFHSMGL PHGVSDAFTR
IKTNLAYFRM NYAIVVLIVI FFSLIWHPTS LIVFTVLVVV WIFLYFLRDE PIKLFRFQID
DRTVLIVLSV LTVVLLLLTN ATFNIVGALV TGAVLVLIHS VVRKTEDLFL DEEAATTETS
GLTSYPST
