PR1_ARATH
ID PR1_ARATH Reviewed; 161 AA.
AC P33154; Q1PF70;
DT 01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1993, sequence version 1.
DT 25-MAY-2022, entry version 149.
DE RecName: Full=Pathogenesis-related protein 1;
DE Short=PR-1;
DE Flags: Precursor;
GN OrderedLocusNames=At2g14610; ORFNames=T6B13.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC STRAIN=cv. Landsberg erecta; TISSUE=Leaf;
RX PubMed=1392589; DOI=10.2307/3869523;
RA Uknes S., Mauch-Mani B., Moyer M., Potter S., Williams S., Dincher S.,
RA Chandler D., Slusarenko A., Ward E., Ryals J.;
RT "Acquired resistance in Arabidopsis.";
RL Plant Cell 4:645-656(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT "Simultaneous high-throughput recombinational cloning of open reading
RT frames in closed and open configurations.";
RL Plant Biotechnol. J. 4:317-324(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Partially responsible for acquired pathogen resistance.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast.
CC -!- INDUCTION: By 2,6-dichloroisonicotinic acid (INA) and salicylic acid
CC (possibly an endogenous signal for acquired resistance). Strongly
CC induced by pathogen infection.
CC -!- SIMILARITY: Belongs to the CRISP family. {ECO:0000305}.
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DR EMBL; M90508; AAA32863.1; -; mRNA.
DR EMBL; AC005398; AAC69381.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06314.1; -; Genomic_DNA.
DR EMBL; DQ446496; ABE65442.1; -; Genomic_DNA.
DR EMBL; AY064023; AAL36379.1; -; mRNA.
DR EMBL; AY117187; AAM51262.1; -; mRNA.
DR PIR; JQ1693; JQ1693.
DR RefSeq; NP_179068.1; NM_127025.3.
DR AlphaFoldDB; P33154; -.
DR SMR; P33154; -.
DR STRING; 3702.AT2G14610.1; -.
DR PaxDb; P33154; -.
DR PRIDE; P33154; -.
DR ProteomicsDB; 226319; -.
DR EnsemblPlants; AT2G14610.1; AT2G14610.1; AT2G14610.
DR GeneID; 815949; -.
DR Gramene; AT2G14610.1; AT2G14610.1; AT2G14610.
DR KEGG; ath:AT2G14610; -.
DR Araport; AT2G14610; -.
DR TAIR; locus:2064294; AT2G14610.
DR eggNOG; KOG3017; Eukaryota.
DR HOGENOM; CLU_035730_8_1_1; -.
DR InParanoid; P33154; -.
DR OMA; YYWVVAR; -.
DR OrthoDB; 1528782at2759; -.
DR PhylomeDB; P33154; -.
DR PRO; PR:P33154; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; P33154; baseline and differential.
DR Genevisible; P33154; AT.
DR GO; GO:0048046; C:apoplast; IEA:UniProtKB-SubCell.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0099503; C:secretory vesicle; HDA:TAIR.
DR GO; GO:0006952; P:defense response; TAS:TAIR.
DR GO; GO:0010266; P:response to vitamin B1; IEP:TAIR.
DR GO; GO:0009414; P:response to water deprivation; IEP:TAIR.
DR GO; GO:0009627; P:systemic acquired resistance; IEP:TAIR.
DR Gene3D; 3.40.33.10; -; 1.
DR InterPro; IPR018244; Allrgn_V5/Tpx1_CS.
DR InterPro; IPR014044; CAP_domain.
DR InterPro; IPR035940; CAP_sf.
DR InterPro; IPR001283; CRISP-related.
DR PANTHER; PTHR10334; PTHR10334; 1.
DR Pfam; PF00188; CAP; 1.
DR PRINTS; PR00837; V5TPXLIKE.
DR SMART; SM00198; SCP; 1.
DR SUPFAM; SSF55797; SSF55797; 1.
DR PROSITE; PS01009; CRISP_1; 1.
DR PROSITE; PS01010; CRISP_2; 1.
PE 1: Evidence at protein level;
KW Apoplast; Direct protein sequencing; Disulfide bond;
KW Pathogenesis-related protein; Plant defense; Reference proteome; Secreted;
KW Signal.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..161
FT /note="Pathogenesis-related protein 1"
FT /id="PRO_0000006304"
FT DOMAIN 34..149
FT /note="SCP"
FT DISULFID 70..138
FT /evidence="ECO:0000250"
FT DISULFID 113..117
FT /evidence="ECO:0000250"
FT DISULFID 133..147
FT /evidence="ECO:0000250"
SQ SEQUENCE 161 AA; 17677 MW; 898B0FF6547C3F84 CRC64;
MNFTGYSRFL IVFVALVGAL VLPSKAQDSP QDYLRVHNQA RGAVGVGPMQ WDERVAAYAR
SYAEQLRGNC RLIHSGGPYG ENLAWGSGDL SGVSAVNMWV SEKANYNYAA NTCNGVCGHY
TQVVWRKSVR LGCAKVRCNN GGTIISCNYD PRGNYVNEKP Y
