PR23C_HUMAN
ID PR23C_HUMAN Reviewed; 262 AA.
AC Q6ZRP0;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=Proline-rich protein 23C;
GN Name=PRR23C;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
CC -!- SIMILARITY: Belongs to the PRR23 family. {ECO:0000305}.
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DR EMBL; AK128089; BAC87269.1; -; mRNA.
DR CCDS; CCDS46924.1; -.
DR RefSeq; NP_001128129.1; NM_001134657.1.
DR AlphaFoldDB; Q6ZRP0; -.
DR STRING; 9606.ENSP00000396648; -.
DR BioMuta; PRR23C; -.
DR DMDM; 74711211; -.
DR PaxDb; Q6ZRP0; -.
DR PeptideAtlas; Q6ZRP0; -.
DR PRIDE; Q6ZRP0; -.
DR DNASU; 389152; -.
DR Ensembl; ENST00000413199.1; ENSP00000396648.1; ENSG00000233701.3.
DR GeneID; 389152; -.
DR KEGG; hsa:389152; -.
DR MANE-Select; ENST00000413199.1; ENSP00000396648.1; NM_001134657.1; NP_001128129.1.
DR UCSC; uc011bmt.1; human.
DR CTD; 389152; -.
DR GeneCards; PRR23C; -.
DR HGNC; HGNC:37173; PRR23C.
DR HPA; ENSG00000233701; Not detected.
DR neXtProt; NX_Q6ZRP0; -.
DR OpenTargets; ENSG00000233701; -.
DR PharmGKB; PA165698175; -.
DR VEuPathDB; HostDB:ENSG00000233701; -.
DR eggNOG; ENOG502RU0G; Eukaryota.
DR GeneTree; ENSGT00390000007772; -.
DR HOGENOM; CLU_090685_0_0_1; -.
DR InParanoid; Q6ZRP0; -.
DR OMA; EFPELWM; -.
DR OrthoDB; 1423797at2759; -.
DR PhylomeDB; Q6ZRP0; -.
DR TreeFam; TF338612; -.
DR PathwayCommons; Q6ZRP0; -.
DR SignaLink; Q6ZRP0; -.
DR BioGRID-ORCS; 389152; 5 hits in 999 CRISPR screens.
DR GenomeRNAi; 389152; -.
DR Pharos; Q6ZRP0; Tdark.
DR PRO; PR:Q6ZRP0; -.
DR Proteomes; UP000005640; Chromosome 3.
DR RNAct; Q6ZRP0; protein.
DR Bgee; ENSG00000233701; Expressed in testis and 3 other tissues.
DR InterPro; IPR018903; PRR23.
DR Pfam; PF10630; DUF2476; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..262
FT /note="Proline-rich protein 23C"
FT /id="PRO_0000332250"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 225..262
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..246
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..262
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 262 AA; 27805 MW; D38B41627D20153A CRC64;
MGSRPCSPSA CLAPWWGQQP GGPGPAKRSR LEEPAGPESR AAPSPEDPAG TPAVDALTSM
VVLDAGCALR VPLEDVDLVL ELAPMSVLRV SLGGHTLIVI PEVLLSSVDE CSGAQGDWSA
GLEVDVFLGA HGEDVVVEQE VCASVPEIAA EEEAYEEDAD SEFPELWMDS AAGSAAGLYP
SARSMFSPYR EGPIRGPCAL APNPSSERRS PRPIFDLEFH LLEPVPSSPL QPLPPSPSPG
PHARPELPER PPCKVRRRLF QE
