PR39B_ARATH
ID PR39B_ARATH Reviewed; 1036 AA.
AC F4KHG8; Q9FL22;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 03-AUG-2022, entry version 72.
DE RecName: Full=Pre-mRNA-processing factor 39-2 {ECO:0000303|PubMed:28971960};
DE Short=AtPRP39-2 {ECO:0000303|PubMed:28971960};
DE AltName: Full=PRP39 homolog B {ECO:0000305};
DE AltName: Full=Pre-mRNA-processing factor 39b {ECO:0000303|PubMed:28971960};
GN Name=PRP39-2 {ECO:0000303|PubMed:28971960};
GN Synonyms=PRP39b {ECO:0000303|PubMed:28971960};
GN OrderedLocusNames=At5g46400 {ECO:0000312|Araport:AT5G46400};
GN ORFNames=MPL12.20 {ECO:0000312|EMBL:BAB11095.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9679202; DOI=10.1093/dnares/5.2.131;
RA Kaneko T., Kotani H., Nakamura Y., Sato S., Asamizu E., Miyajima N.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. V. Sequence
RT features of the regions of 1,381,565 bp covered by twenty one physically
RT assigned P1 and TAC clones.";
RL DNA Res. 5:131-145(1998).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP GENE FAMILY, AND NOMENCLATURE.
RC STRAIN=cv. Columbia;
RX PubMed=28971960; DOI=10.1534/genetics.117.300149;
RA Kanno T., Lin W.-D., Fu J.L., Chang C.-L., Matzke A.J.M., Matzke M.;
RT "A genetic screen for pre-mRNA splicing mutants of Arabidopsis thaliana
RT identifies putative U1 snRNP components RBM25 and PRP39a.";
RL Genetics 207:1347-1359(2017).
CC -!- FUNCTION: Involved in pre-mRNA splicing.
CC {ECO:0000250|UniProtKB:Q93ZR3}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:P39682}.
CC -!- SIMILARITY: Belongs to the PRP39 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB11095.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AB010698; BAB11095.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002688; AED95379.1; -; Genomic_DNA.
DR RefSeq; NP_199452.2; NM_124010.3.
DR AlphaFoldDB; F4KHG8; -.
DR SMR; F4KHG8; -.
DR STRING; 3702.AT5G46400.1; -.
DR iPTMnet; Q9FL22; -.
DR PaxDb; F4KHG8; -.
DR PRIDE; F4KHG8; -.
DR ProteomicsDB; 199352; -.
DR EnsemblPlants; AT5G46400.1; AT5G46400.1; AT5G46400.
DR GeneID; 834683; -.
DR Gramene; AT5G46400.1; AT5G46400.1; AT5G46400.
DR Araport; AT5G46400; -.
DR TAIR; locus:2170453; AT5G46400.
DR eggNOG; KOG1258; Eukaryota.
DR HOGENOM; CLU_007864_0_0_1; -.
DR InParanoid; F4KHG8; -.
DR OMA; KEKIKCR; -.
DR OrthoDB; 887474at2759; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; F4KHG8; baseline and differential.
DR GO; GO:0000243; C:commitment complex; IBA:GO_Central.
DR GO; GO:0005685; C:U1 snRNP; IBA:GO_Central.
DR GO; GO:0071004; C:U2-type prespliceosome; IBA:GO_Central.
DR GO; GO:0000395; P:mRNA 5'-splice site recognition; IBA:GO_Central.
DR Gene3D; 1.25.40.10; -; 2.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR SMART; SM00386; HAT; 4.
DR SUPFAM; SSF48452; SSF48452; 2.
PE 3: Inferred from homology;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome; Repeat.
FT CHAIN 1..1036
FT /note="Pre-mRNA-processing factor 39-2"
FT /id="PRO_0000454966"
FT REPEAT 62..94
FT /note="HAT 1"
FT /evidence="ECO:0000255"
FT REPEAT 96..128
FT /note="HAT 2"
FT /evidence="ECO:0000255"
FT REPEAT 131..166
FT /note="HAT 3"
FT /evidence="ECO:0000255"
FT REPEAT 168..201
FT /note="HAT 4"
FT /evidence="ECO:0000255"
FT REPEAT 278..310
FT /note="HAT 5"
FT /evidence="ECO:0000255"
FT REPEAT 312..344
FT /note="HAT 6"
FT /evidence="ECO:0000255"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 595..618
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 714..767
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 995..1036
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 714..731
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..754
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1036 AA; 118658 MW; 803D10A71DBE5F96 CRC64;
MVTTEVRTAV SDKEPLQRSP ELDSSTDFLD NDRLKETFSS GALDFDEWTL LISEIETTSF
PDDIEKLCLV YDAFLLEFPL CHGYWRKYAY HKIKLCTLED AVEVFERAVQ AATYSVAVWL
DYCAFAVAAY EDPHDVSRLF ERGLSFIGKD YSCCTLWDKY IEYLLGQQQW SSLANVYLRT
LKYPSKKLDL YYKNFRKIAA SLKEKIKCRI DVNGDLSSDP MEEDLVHTRH TDEEISIVVR
ELMGPSSSSA VSKALHTYLS IGEQFYQDSR QLMEKISCFE TQIRRPYFHV KPLDTNQLDN
WHAYLSFGET YGDFDWAINL YERCLIPCAN YTEFWFRYVD FVESKGGREL ANFALARASQ
TFVKSASVIH LFNARFKEHV GDASAASVAL SRCGEELGFG FVENVTKKAN MEKRLGNFEA
AVTTYREALN KTLIGKENLE TTARLYVQFS RLKYVITNSA DDAAQILLEG NENVPHCKLL
LEELMRLLMM HGGSRQVDLL DPIIDKELSH QADSSDGLSA EDKEEISNLY MEFIDLSGTI
HDVRKALGRH IKLFPHSARA KLRGSRPSGN LFRELIQRRE KTRERLNQDL LTNKGISSIV
DSPPKEKKES SLDSYGTQSK DAVRADYVNT EPNQGCLTSG HLVEGNDNVI ERETLCESQS
DLSMGLKANE GGKRSHEVSL PIQASPEHGF VTKQAHFSSN SVDTVKSDAI VIQPSGSQSP
QSYQSQESLR QTGRNRYHRR DLNQMHRDSK PRSQERPPQM PYSPVGTGRE ILGQHMAFTH
QDNRVALQSS TSQNPQNQFQ NSALQMHPVV QTSNAYPQSQ IHGQHMIVSP PESQNPQNQC
QNSTSQVQTS FAYPQTQIPQ NPVQSNYQQE GQMQSHEAYN QMWQQYYYSY YYYQQQQQLM
SEQPQPNQNP QPQLDQNLVQ LLSKQYQSQA KTQYLQPQQV EQVNTQQQSQ EPQNQQQIQF
QQQQQQQEWF QQQQQWQQQQ YLLYIQQQQL QGEAKGDEQR LSMPQGSTTN SDIQKSQESG
AVNEANLSSD TSISSI
