PR5_ARATH
ID PR5_ARATH Reviewed; 239 AA.
AC P28493;
DT 01-DEC-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-1992, sequence version 1.
DT 25-MAY-2022, entry version 139.
DE RecName: Full=Pathogenesis-related protein 5;
DE Short=PR-5;
DE Flags: Precursor;
GN OrderedLocusNames=At1g75040; ORFNames=F9E10.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND PARTIAL PROTEIN SEQUENCE.
RC STRAIN=cv. Landsberg erecta; TISSUE=Leaf;
RX PubMed=1392589; DOI=10.2307/3869523;
RA Uknes S., Mauch-Mani B., Moyer M., Potter S., Williams S., Dincher S.,
RA Chandler D., Slusarenko A., Ward E., Ryals J.;
RT "Acquired resistance in Arabidopsis.";
RL Plant Cell 4:645-656(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=cv. C24; TISSUE=Flower;
RA Arro M., Richard L., Than Van K.T., Ferrer A., Boronat A.;
RT "Cloning and characterization of a novel cDNA encoding thaumatin-like
RT protein PR5 from Arabidopsis thaliana.";
RL (er) Plant Gene Register PGR97-053(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Partially responsible for acquired pathogen resistance.
CC -!- SUBCELLULAR LOCATION: Secreted, extracellular space, apoplast.
CC Note=Accumulates in the apoplast before secretion.
CC -!- INDUCTION: By 2,6-dichloroisonicotinic acid (INA) and salicylic acid
CC (possibly an endogenous signal for acquired resistance). Strongly
CC induced by pathogen infection.
CC -!- SIMILARITY: Belongs to the thaumatin family. {ECO:0000255|PROSITE-
CC ProRule:PRU00699}.
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DR EMBL; M90510; AAA32865.1; -; mRNA.
DR EMBL; L78079; AAB68336.1; -; mRNA.
DR EMBL; AC013258; AAG51923.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE35665.1; -; Genomic_DNA.
DR EMBL; AY035168; AAK59672.1; -; mRNA.
DR EMBL; AY059114; AAL15220.1; -; mRNA.
DR PIR; JQ1695; JQ1695.
DR RefSeq; NP_177641.1; NM_106161.3.
DR AlphaFoldDB; P28493; -.
DR SMR; P28493; -.
DR IntAct; P28493; 1.
DR STRING; 3702.AT1G75040.1; -.
DR PaxDb; P28493; -.
DR PRIDE; P28493; -.
DR ProteomicsDB; 226336; -.
DR EnsemblPlants; AT1G75040.1; AT1G75040.1; AT1G75040.
DR GeneID; 843842; -.
DR Gramene; AT1G75040.1; AT1G75040.1; AT1G75040.
DR KEGG; ath:AT1G75040; -.
DR Araport; AT1G75040; -.
DR TAIR; locus:2037235; AT1G75040.
DR eggNOG; ENOG502QUEJ; Eukaryota.
DR HOGENOM; CLU_043181_0_1_1; -.
DR InParanoid; P28493; -.
DR OMA; ERFNTDQ; -.
DR OrthoDB; 1135904at2759; -.
DR PhylomeDB; P28493; -.
DR PRO; PR:P28493; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; P28493; baseline and differential.
DR Genevisible; P28493; AT.
DR GO; GO:0048046; C:apoplast; HDA:TAIR.
DR GO; GO:0005739; C:mitochondrion; HDA:TAIR.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0099503; C:secretory vesicle; HDA:TAIR.
DR GO; GO:0003729; F:mRNA binding; IDA:TAIR.
DR GO; GO:0006952; P:defense response; IBA:GO_Central.
DR GO; GO:0031540; P:regulation of anthocyanin biosynthetic process; IEP:TAIR.
DR GO; GO:0046686; P:response to cadmium ion; IEP:TAIR.
DR GO; GO:0010224; P:response to UV-B; IGI:TAIR.
DR GO; GO:0009615; P:response to virus; IEP:TAIR.
DR GO; GO:0009627; P:systemic acquired resistance; IEP:TAIR.
DR Gene3D; 2.60.110.10; -; 1.
DR InterPro; IPR037176; Osmotin/thaumatin-like_sf.
DR InterPro; IPR001938; Thaumatin.
DR InterPro; IPR017949; Thaumatin_CS.
DR PANTHER; PTHR31048; PTHR31048; 1.
DR Pfam; PF00314; Thaumatin; 1.
DR PIRSF; PIRSF002703; Thaumatin; 1.
DR PRINTS; PR00347; THAUMATIN.
DR SMART; SM00205; THN; 1.
DR SUPFAM; SSF49870; SSF49870; 1.
DR PROSITE; PS00316; THAUMATIN_1; 1.
DR PROSITE; PS51367; THAUMATIN_2; 1.
PE 1: Evidence at protein level;
KW Apoplast; Direct protein sequencing; Disulfide bond;
KW Pathogenesis-related protein; Plant defense; Reference proteome; Secreted;
KW Signal.
FT SIGNAL 1..23
FT CHAIN 24..239
FT /note="Pathogenesis-related protein 5"
FT /id="PRO_0000034036"
FT DISULFID 32..238
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 79..89
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 94..99
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 146..228
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 151..211
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 159..174
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 178..187
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
FT DISULFID 188..198
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00699"
SQ SEQUENCE 239 AA; 25252 MW; CB376F61506ED093 CRC64;
MANISSIHIL FLVFITSGIA VMATDFTLRN NCPTTVWAGT LAGQGPKLGD GGFELTPGAS
RQLTAPAGWS GRFWARTGCN FDASGNGRCV TGDCGGLRCN GGGVPPVTLA EFTLVGDGGK
DFYDVSLVDG YNVKLGIRPS GGSGDCKYAG CVSDLNAACP DMLKVMDQNN VVACKSACER
FNTDQYCCRG ANDKPETCPP TDYSRIFKNA CPDAYSYAYD DETSTFTCTG ANYEITFCP