ID   PRA1_USTHO              Reviewed;         359 AA.
AC   Q99063;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Pheromone receptor 1;
GN   Name=PRA1;
OS   Ustilago hordei (Barley covered smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=120017;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=UH112;
RX   PubMed=7913746; DOI=10.1073/pnas.91.15.7085;
RA   Bakkeren G., Kronstad J.W.;
RT   "Linkage of mating-type loci distinguishes bipolar from tetrapolar mating
RT   in basidiomycetous smut fungi.";
RL   Proc. Natl. Acad. Sci. U.S.A. 91:7085-7089(1994).
CC   -!- FUNCTION: Receptor for the A2 pheromone, a prenylated mating factor.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 4 family.
CC       {ECO:0000305}.
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DR   EMBL; U07939; AAA19965.1; -; Genomic_DNA.
DR   PIR; A57718; A57718.
DR   AlphaFoldDB; Q99063; -.
DR   SMR; Q99063; -.
DR   PRIDE; Q99063; -.
DR   OMA; AVYCILS; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004933; F:mating-type a-factor pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR   InterPro; IPR001546; GPCR_Pheromne_A_rcpt.
DR   InterPro; IPR001499; GPCR_STE3.
DR   PANTHER; PTHR28097; PTHR28097; 1.
DR   Pfam; PF02076; STE3; 1.
DR   PRINTS; PR00899; GPCRSTE3.
DR   PRINTS; PR00900; PHEROMONEAR.
PE   3: Inferred from homology;
KW   G-protein coupled receptor; Membrane; Pheromone response; Receptor;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..359
FT                   /note="Pheromone receptor 1"
FT                   /id="PRO_0000195076"
FT   TRANSMEM        5..25
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        33..53
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..87
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..130
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        206..226
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        268..288
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   REGION          335..359
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   359 AA;  40452 MW;  BB7E60A7B5C76BAC CRC64;
     MLDHVTPFFA LFACILVLFA LGWHIRSRNV GTITLSLYLF FGNLDNFVNS VAWWSTAEDK
     APGFCEVSIR LRHALYIAIP ASNLVIARKL ESIASTRQVR ASASEHKKSI IIDLLISVGL
     PVLYVSLMIV NQTNRYGIIE QVGCWPFLSL SWVWVLLVAA PVLIVSFASA VYSVLAFRWF
     WIRRRQFQAV LASSASTLNK ARYIRLLVLT AIDMLLFFPI YVGSVSDTIR GAITTSYVSW
     SYVHTGFSYI PQFSAEVMEM QPSFKARLIL SRLVCPISAY IFFAMFGLGQ EARQGYKHAV
     LKALVFCKLR KERQKPIQNH IVANIEVVTF QSRETSGGID GSPHSEKFSI NTPTKYEEA