ID   PRA1_USTMA              Reviewed;         357 AA.
AC   P31302; A0A0D1E644; Q4PBY0;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Pheromone receptor 1;
GN   Name=PRA1; ORFNames=UMAG_02383;
OS   Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=237631;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1310895; DOI=10.1016/0092-8674(92)90182-c;
RA   Boelker M., Urban M., Kahmann R.;
RT   "The a mating type locus of U. maydis specifies cell signaling
RT   components.";
RL   Cell 68:441-450(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=521 / FGSC 9021;
RX   PubMed=17080091; DOI=10.1038/nature05248;
RA   Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., Saville B.J.,
RA   Banuett F., Kronstad J.W., Gold S.E., Mueller O., Perlin M.H.,
RA   Woesten H.A.B., de Vries R., Ruiz-Herrera J., Reynaga-Pena C.G.,
RA   Snetselaar K., McCann M., Perez-Martin J., Feldbruegge M., Basse C.W.,
RA   Steinberg G., Ibeas J.I., Holloman W., Guzman P., Farman M.L.,
RA   Stajich J.E., Sentandreu R., Gonzalez-Prieto J.M., Kennell J.C., Molina L.,
RA   Schirawski J., Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N.,
RA   Scherer M., Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B.,
RA   Meng S., Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J.,
RA   Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P.,
RA   Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G.,
RA   Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A.,
RA   Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., Muensterkoetter M.,
RA   Haase D., Oesterheld M., Mewes H.-W., Mauceli E.W., DeCaprio D., Wade C.M.,
RA   Butler J., Young S.K., Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E.,
RA   Birren B.W.;
RT   "Insights from the genome of the biotrophic fungal plant pathogen Ustilago
RT   maydis.";
RL   Nature 444:97-101(2006).
RN   [3]
RP   GENOME REANNOTATION.
RC   STRAIN=521 / FGSC 9021;
RA   Gueldener U., Muensterkoetter M., Walter M.C., Mannhaupt G., Kahmann R.;
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Receptor for the A2 pheromone, a prenylated mating factor.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 4 family.
CC       {ECO:0000305}.
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DR   EMBL; M84157; AAA34228.1; -; Genomic_DNA.
DR   EMBL; U37795; AAA99766.1; -; Genomic_DNA.
DR   EMBL; CM003144; KIS69865.1; -; Genomic_DNA.
DR   PIR; C42087; C42087.
DR   RefSeq; XP_011388683.1; XM_011390381.1.
DR   AlphaFoldDB; P31302; -.
DR   STRING; 5270.UM02383P0; -.
DR   EnsemblFungi; KIS69865; KIS69865; UMAG_02383.
DR   GeneID; 23563142; -.
DR   KEGG; uma:UMAG_02383; -.
DR   VEuPathDB; FungiDB:UMAG_02383; -.
DR   eggNOG; ENOG502S44N; Eukaryota.
DR   HOGENOM; CLU_027592_0_1_1; -.
DR   InParanoid; P31302; -.
DR   OMA; AVYCILS; -.
DR   OrthoDB; 730409at2759; -.
DR   Proteomes; UP000000561; Chromosome 5.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   GO; GO:0004933; F:mating-type a-factor pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0004932; F:mating-type factor pheromone receptor activity; IBA:GO_Central.
DR   GO; GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:GO_Central.
DR   InterPro; IPR001546; GPCR_Pheromne_A_rcpt.
DR   InterPro; IPR001499; GPCR_STE3.
DR   PANTHER; PTHR28097; PTHR28097; 1.
DR   Pfam; PF02076; STE3; 1.
DR   PRINTS; PR00899; GPCRSTE3.
DR   PRINTS; PR00900; PHEROMONEAR.
PE   3: Inferred from homology;
KW   G-protein coupled receptor; Membrane; Pheromone response; Receptor;
KW   Reference proteome; Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..357
FT                   /note="Pheromone receptor 1"
FT                   /id="PRO_0000195077"
FT   TRANSMEM        5..25
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..52
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        67..90
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        110..130
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        145..165
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        206..226
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        268..288
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
FT   REGION          338..357
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   357 AA;  40285 MW;  31A1470EAB44EBC5 CRC64;
     MLDHITPFFA LVAFFLVLMP FAWHIKSKNV GLIMLSIWLM LGNLDNFVNS MVWWKTTADL
     APAYCELSVR LRHLLFIAIP ASNLAIARKL ESIASTRQVR AGPGDHRRAV IIDLLICLGI
     PIIYTSLMIV NQSNRYGILE EAGCWPMMVF SWLWVLLVAA PVIVVSLCSA VYSALAFRWF
     WVRRRQFQAV LASSASTINR SHYVRLLLLT AIDMLLFFPI YVGTIAAQIK SSISIPYGSW
     SSVHTGFNQI PQYPASLVLM ENTFQRNLIL ARLVCPLSAY IFFAMFGLGL EVRQGYKEAF
     HRALLFCRLR KEPKASALQH VVADIEVVTF RSHDTFDANT STKSEKSDID MRGSEAA