ID   PRA26_HUMAN             Reviewed;         382 AA.
AC   H0Y7S4;
DT   11-DEC-2013, integrated into UniProtKB/Swiss-Prot.
DT   11-DEC-2013, sequence version 2.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Putative PRAME family member 26 {ECO:0000305};
GN   Name=PRAMEF26 {ECO:0000312|HGNC:HGNC:49178};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16710414; DOI=10.1038/nature04727;
RA   Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D., Dunham A.,
RA   Scott C.E., Howe K.L., Woodfine K., Spencer C.C.A., Jones M.C., Gillson C.,
RA   Searle S., Zhou Y., Kokocinski F., McDonald L., Evans R., Phillips K.,
RA   Atkinson A., Cooper R., Jones C., Hall R.E., Andrews T.D., Lloyd C.,
RA   Ainscough R., Almeida J.P., Ambrose K.D., Anderson F., Andrew R.W.,
RA   Ashwell R.I.S., Aubin K., Babbage A.K., Bagguley C.L., Bailey J.,
RA   Beasley H., Bethel G., Bird C.P., Bray-Allen S., Brown J.Y., Brown A.J.,
RA   Buckley D., Burton J., Bye J., Carder C., Chapman J.C., Clark S.Y.,
RA   Clarke G., Clee C., Cobley V., Collier R.E., Corby N., Coville G.J.,
RA   Davies J., Deadman R., Dunn M., Earthrowl M., Ellington A.G., Errington H.,
RA   Frankish A., Frankland J., French L., Garner P., Garnett J., Gay L.,
RA   Ghori M.R.J., Gibson R., Gilby L.M., Gillett W., Glithero R.J.,
RA   Grafham D.V., Griffiths C., Griffiths-Jones S., Grocock R., Hammond S.,
RA   Harrison E.S.I., Hart E., Haugen E., Heath P.D., Holmes S., Holt K.,
RA   Howden P.J., Hunt A.R., Hunt S.E., Hunter G., Isherwood J., James R.,
RA   Johnson C., Johnson D., Joy A., Kay M., Kershaw J.K., Kibukawa M.,
RA   Kimberley A.M., King A., Knights A.J., Lad H., Laird G., Lawlor S.,
RA   Leongamornlert D.A., Lloyd D.M., Loveland J., Lovell J., Lush M.J.,
RA   Lyne R., Martin S., Mashreghi-Mohammadi M., Matthews L., Matthews N.S.W.,
RA   McLaren S., Milne S., Mistry S., Moore M.J.F., Nickerson T., O'Dell C.N.,
RA   Oliver K., Palmeiri A., Palmer S.A., Parker A., Patel D., Pearce A.V.,
RA   Peck A.I., Pelan S., Phelps K., Phillimore B.J., Plumb R., Rajan J.,
RA   Raymond C., Rouse G., Saenphimmachak C., Sehra H.K., Sheridan E.,
RA   Shownkeen R., Sims S., Skuce C.D., Smith M., Steward C., Subramanian S.,
RA   Sycamore N., Tracey A., Tromans A., Van Helmond Z., Wall M., Wallis J.M.,
RA   White S., Whitehead S.L., Wilkinson J.E., Willey D.L., Williams H.,
RA   Wilming L., Wray P.W., Wu Z., Coulson A., Vaudin M., Sulston J.E.,
RA   Durbin R.M., Hubbard T., Wooster R., Dunham I., Carter N.P., McVean G.,
RA   Ross M.T., Harrow J., Olson M.V., Beck S., Rogers J., Bentley D.R.;
RT   "The DNA sequence and biological annotation of human chromosome 1.";
RL   Nature 441:315-321(2006).
CC   -!- SIMILARITY: Belongs to the PRAME family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
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DR   EMBL; CR589903; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; H0Y7S4; -.
DR   iPTMnet; H0Y7S4; -.
DR   PhosphoSitePlus; H0Y7S4; -.
DR   SwissPalm; H0Y7S4; -.
DR   BioMuta; PRAMEF26; -.
DR   MassIVE; H0Y7S4; -.
DR   PaxDb; H0Y7S4; -.
DR   PeptideAtlas; H0Y7S4; -.
DR   PRIDE; H0Y7S4; -.
DR   GeneCards; PRAMEF26; -.
DR   HGNC; HGNC:49178; PRAMEF26.
DR   neXtProt; NX_H0Y7S4; -.
DR   InParanoid; H0Y7S4; -.
DR   TreeFam; TF332708; -.
DR   PathwayCommons; H0Y7S4; -.
DR   Pharos; H0Y7S4; Tdark.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; H0Y7S4; protein.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR032675; LRR_dom_sf.
PE   5: Uncertain;
KW   Leucine-rich repeat; Reference proteome; Repeat.
FT   CHAIN           1..382
FT                   /note="Putative PRAME family member 26"
FT                   /id="PRO_0000424822"
FT   REPEAT          3..30
FT                   /note="LRR 1; degenerate"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          85..109
FT                   /note="LRR 2; degenerate"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          110..136
FT                   /note="LRR 3; degenerate"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          137..172
FT                   /note="LRR 4; degenerate"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          173..198
FT                   /note="LRR 5"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          199..230
FT                   /note="LRR 6"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          231..251
FT                   /note="LRR 7"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          255..282
FT                   /note="LRR 8"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
FT   REPEAT          283..307
FT                   /note="LRR 9"
FT                   /evidence="ECO:0000250|UniProtKB:Q3UWY1"
SQ   SEQUENCE   382 AA;  44302 MW;  60350D37BA831D1F CRC64;
     MVRWKLQVLD LQDVCENFWM VWSEAMARGC FLNAKRNKKP VQDCPRMRGR QPLTVFVELW
     LKNRTLDEHL TCLLLWVKQR KDLLHLCCKK LKILGMPFRN IRSILKMVNL DCIQEVEVNC
     KWVLPILTQF TPYLGHMRNL QKLVLSHMDV SRYVSPEQKK EIVTQFTTQF LKLHCLQKLY
     MNSVSFLEGH LDQLLSCLKT SLKVLTITNC VLLESDLKHL SQCPSISQLK TLDLSGIRLT
     NYSLVPLQIL LEKVAATLEY LDLDDCGIID SQVNAILPAL SRCFELNTFS FCGNPISMAT
     LENLLSHTII LKNLCLELYP APRESYGADG TLCWSRFTQI RAELMKRVRD LRHPKRILFG
     TDYCPDCGNR SFYDLEADQY CC