ID   PRA2_USTMD              Reviewed;         346 AA.
AC   P31303;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Pheromone receptor 2;
GN   Name=PRA2;
OS   Ustilago maydis (Corn smut fungus).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina;
OC   Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago.
OX   NCBI_TaxID=5270;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FBD11-21;
RX   PubMed=1310895; DOI=10.1016/0092-8674(92)90182-c;
RA   Boelker M., Urban M., Kahmann R.;
RT   "The a mating type locus of U. maydis specifies cell signaling
RT   components.";
RL   Cell 68:441-450(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=FBD11-21;
RX   PubMed=8602158; DOI=10.1007/bf02174029;
RA   Urban M., Kahmann R., Boelker M.;
RT   "The biallelic a mating type locus of Ustilago maydis: remnants of an
RT   additional pheromone gene indicate evolution from a multiallelic
RT   ancestor.";
RL   Mol. Gen. Genet. 250:414-420(1996).
CC   -!- FUNCTION: Receptor for the A1 pheromone, a prenylated mating factor.
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the G-protein coupled receptor 4 family.
CC       {ECO:0000305}.
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DR   EMBL; U37796; AAA99768.1; -; Genomic_DNA.
DR   PIR; D42087; D42087.
DR   PIR; S64693; S64693.
DR   AlphaFoldDB; P31303; -.
DR   VEuPathDB; FungiDB:UMAG_02383; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004933; F:mating-type a-factor pheromone receptor activity; IEA:InterPro.
DR   GO; GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
DR   InterPro; IPR001546; GPCR_Pheromne_A_rcpt.
DR   InterPro; IPR001499; GPCR_STE3.
DR   PANTHER; PTHR28097; PTHR28097; 1.
DR   Pfam; PF02076; STE3; 1.
DR   PRINTS; PR00899; GPCRSTE3.
DR   PRINTS; PR00900; PHEROMONEAR.
PE   3: Inferred from homology;
KW   G-protein coupled receptor; Membrane; Pheromone response; Receptor;
KW   Transducer; Transmembrane; Transmembrane helix.
FT   CHAIN           1..346
FT                   /note="Pheromone receptor 2"
FT                   /id="PRO_0000195078"
FT   TRANSMEM        8..28
FT                   /note="Helical; Name=1"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        34..54
FT                   /note="Helical; Name=2"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        71..94
FT                   /note="Helical; Name=3"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        115..135
FT                   /note="Helical; Name=4"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        160..180
FT                   /note="Helical; Name=5"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        219..239
FT                   /note="Helical; Name=6"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        270..290
FT                   /note="Helical; Name=7"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   346 AA;  38781 MW;  D9533413E3951E10 CRC64;
     MFSGKENVSF GVLCLLAGCI STSSCLIHLQ AKNIGVLLMM FWCFTGLVNK GINALAFNNS
     LRLAWTLGCD LSAIIERTWQ FGLCCSALCV LQRLEGIASL RQAHSTVWDR KRRLLIDFGV
     GLGLPALQIP MFFIVQPYRL NVIENIGCSA PLYASVPALF IYHLWRLLVS LVCAVYAVLV
     LRWFMLRRRQ FTAALSSQHS GLSQKKYFRL FALAICERVL VSAGQFYVII QSLQIGGLLP
     YTSWAEVHTN FNRILFVPVD TIAHSSLLSL SILRWFSLTP AMALFVFFGL TEEAQSVYKA
     RWKALINLCS SKGKKQTDGR ESLDLEAFES HGSKFSVLVQ RDTVIC