PRB1_ARATH
ID PRB1_ARATH Reviewed; 161 AA.
AC Q9ZNS4;
DT 04-FEB-2015, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Pathogenesis-related protein 1 {ECO:0000303|PubMed:11725949};
DE Short=AtPRB1 {ECO:0000303|PubMed:11725949};
DE Flags: Precursor;
GN Name=PRB1 {ECO:0000303|PubMed:11725949};
GN Synonyms=PR1 {ECO:0000303|PubMed:12529537};
GN OrderedLocusNames=At2g14580 {ECO:0000312|Araport:AT2G14580};
GN ORFNames=T13P21.4 {ECO:0000312|EMBL:AAM15107.1},
GN T6B13 {ECO:0000312|EMBL:AAC69384.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP TISSUE SPECIFICITY, AND INDUCTION BY JASMONIC ACID; ETHYLENE AND SALICYLIC
RP ACID.
RC STRAIN=cv. Columbia, and cv. Wassilewskija;
RX PubMed=11725949; DOI=10.1023/a:1012410009930;
RA Santamaria M., Thomson C.J., Read N.D., Loake G.J.;
RT "The promoter of a basic PR1-like gene, AtPRB1, from Arabidopsis
RT establishes an organ-specific expression pattern and responsiveness to
RT ethylene and methyl jasmonate.";
RL Plant Mol. Biol. 47:641-652(2001).
RN [4]
RP INDUCTION BY PSEUDOMONAS SYRINGAE.
RX PubMed=12618363; DOI=10.1101/gr.552003;
RA Kim H., Snesrud E.C., Haas B., Cheung F., Town C.D., Quackenbush J.;
RT "Gene expression analyses of Arabidopsis chromosome 2 using a genomic DNA
RT amplicon microarray.";
RL Genome Res. 13:327-340(2003).
RN [5]
RP INDUCTION BY WOUNDING; JASMONIC ACID; ETHYLENE AND SALICYLIC ACID.
RX PubMed=12529537; DOI=10.1104/pp.011015;
RA Mikkelsen M.D., Petersen B.L., Glawischnig E., Jensen A.B., Andreasson E.,
RA Halkier B.A.;
RT "Modulation of CYP79 genes and glucosinolate profiles in Arabidopsis by
RT defense signaling pathways.";
RL Plant Physiol. 131:298-308(2003).
RN [6]
RP INDUCTION BY PLUTELLA XYLOSTELLA; WOUNDING; ETHYLENE; SALICYLIC ACID AND
RP JASMONIC ACID.
RX PubMed=18400103; DOI=10.1186/1471-2164-9-154;
RA Ehlting J., Chowrira S.G., Mattheus N., Aeschliman D.S., Arimura G.,
RA Bohlmann J.;
RT "Comparative transcriptome analysis of Arabidopsis thaliana infested by
RT diamond back moth (Plutella xylostella) larvae reveals signatures of stress
RT response, secondary metabolism, and signalling.";
RL BMC Genomics 9:154-154(2008).
CC -!- FUNCTION: Probably involved in the defense reaction of plants against
CC pathogens. {ECO:0000250|UniProtKB:P04284}.
CC -!- TISSUE SPECIFICITY: Expressed in flowers, stems and roots but not in
CC leaves. {ECO:0000269|PubMed:11725949}.
CC -!- INDUCTION: Accumulates in root tissue in response to ethylene (ET, ACC)
CC and methyl jasmonate (MeJA) (PubMed:11725949, PubMed:12529537,
CC PubMed:18400103). Stimulated by the salicylic acid analog 2,6-dichloro-
CC isonicotinic acid (INA) (PubMed:12529537, PubMed:18400103). Expressed
CC after wounding (PubMed:12529537, PubMed:18400103). Repressed in
CC response to salicylic acid treatment (PubMed:11725949). Strongly
CC induced in response to the incompatible bacterial pathogen Pseudomonas
CC syringae pv. tomato DC3000 (avrRpt2) but only weakly by the compatible
CC strain P.syringae DC3000 (PubMed:12618363). First down-regulated early
CC during diamond back moth (Plutella xylostella) larvae (DBM) feeding
CC before being up-regulated after 24 h (PubMed:18400103).
CC {ECO:0000269|PubMed:11725949, ECO:0000269|PubMed:12529537,
CC ECO:0000269|PubMed:12618363, ECO:0000269|PubMed:18400103}.
CC -!- SIMILARITY: Belongs to the CRISP family. {ECO:0000305}.
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DR EMBL; AC005398; AAC69384.1; -; Genomic_DNA.
DR EMBL; AC006067; AAM15107.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06313.1; -; Genomic_DNA.
DR PIR; H84518; H84518.
DR RefSeq; NP_179064.1; NM_127021.3.
DR AlphaFoldDB; Q9ZNS4; -.
DR SMR; Q9ZNS4; -.
DR STRING; 3702.AT2G14580.1; -.
DR PaxDb; Q9ZNS4; -.
DR PRIDE; Q9ZNS4; -.
DR ProteomicsDB; 226409; -.
DR EnsemblPlants; AT2G14580.1; AT2G14580.1; AT2G14580.
DR GeneID; 815945; -.
DR Gramene; AT2G14580.1; AT2G14580.1; AT2G14580.
DR KEGG; ath:AT2G14580; -.
DR Araport; AT2G14580; -.
DR TAIR; locus:2055240; AT2G14580.
DR eggNOG; KOG3017; Eukaryota.
DR HOGENOM; CLU_035730_8_1_1; -.
DR InParanoid; Q9ZNS4; -.
DR OMA; NTVYIVC; -.
DR OrthoDB; 1528782at2759; -.
DR PhylomeDB; Q9ZNS4; -.
DR PRO; PR:Q9ZNS4; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9ZNS4; baseline and differential.
DR Genevisible; Q9ZNS4; AT.
DR GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR GO; GO:0098542; P:defense response to other organism; IEP:UniProtKB.
DR GO; GO:0009617; P:response to bacterium; IEP:UniProtKB.
DR GO; GO:0009723; P:response to ethylene; IEP:UniProtKB.
DR GO; GO:0080027; P:response to herbivore; IEP:UniProtKB.
DR GO; GO:0009753; P:response to jasmonic acid; IEP:UniProtKB.
DR GO; GO:0009751; P:response to salicylic acid; IEP:UniProtKB.
DR GO; GO:0009611; P:response to wounding; IEP:UniProtKB.
DR Gene3D; 3.40.33.10; -; 1.
DR InterPro; IPR018244; Allrgn_V5/Tpx1_CS.
DR InterPro; IPR014044; CAP_domain.
DR InterPro; IPR035940; CAP_sf.
DR InterPro; IPR001283; CRISP-related.
DR PANTHER; PTHR10334; PTHR10334; 1.
DR Pfam; PF00188; CAP; 1.
DR PRINTS; PR00837; V5TPXLIKE.
DR SMART; SM00198; SCP; 1.
DR SUPFAM; SSF55797; SSF55797; 1.
DR PROSITE; PS01009; CRISP_1; 1.
DR PROSITE; PS01010; CRISP_2; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Plant defense; Reference proteome; Signal.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..161
FT /note="Pathogenesis-related protein 1"
FT /evidence="ECO:0000255"
FT /id="PRO_0000431741"
FT DOMAIN 34..149
FT /note="SCP"
FT /evidence="ECO:0000255"
FT DISULFID 70..138
FT /evidence="ECO:0000250|UniProtKB:P04284"
FT DISULFID 113..117
FT /evidence="ECO:0000250|UniProtKB:P04284"
FT DISULFID 133..147
FT /evidence="ECO:0000250|UniProtKB:P04284"
SQ SEQUENCE 161 AA; 17543 MW; 48FC7A71FE25736B CRC64;
MKVTSYSRIL IILAALVGAL VVPLKAQDSQ QDYVNAHNQA RSQIGVGPMQ WDEGLAAYAR
NYANQLKGDC RLVHSRGPYG ENLAKSGGDL SGVAAVNLWV NEKANYNYDT NTCNGVCGHY
TQVVWRNSVR LGCAKVRCNN GGTIISCNYD PPGNYANQKP Y
