ID   PRCA1_BOVIN             Reviewed;         376 AA.
AC   A7E371;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 2.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Protein PROCA1;
GN   Name=PROCA1;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hereford;
RX   PubMed=19390049; DOI=10.1126/science.1169588;
RG   The bovine genome sequencing and analysis consortium;
RT   "The genome sequence of taurine cattle: a window to ruminant biology and
RT   evolution.";
RL   Science 324:522-528(2009).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-251.
RC   STRAIN=Hereford; TISSUE=Fetal medulla;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the PROCA1 family. {ECO:0000305}.
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DR   EMBL; BC151740; AAI51741.1; -; mRNA.
DR   RefSeq; NP_001160040.1; NM_001166568.1.
DR   AlphaFoldDB; A7E371; -.
DR   SMR; A7E371; -.
DR   STRING; 9913.ENSBTAP00000044327; -.
DR   PaxDb; A7E371; -.
DR   PRIDE; A7E371; -.
DR   Ensembl; ENSBTAT00000047094; ENSBTAP00000044327; ENSBTAG00000017268.
DR   GeneID; 510175; -.
DR   KEGG; bta:510175; -.
DR   CTD; 147011; -.
DR   VEuPathDB; HostDB:ENSBTAG00000017268; -.
DR   VGNC; VGNC:33358; PROCA1.
DR   eggNOG; ENOG502QTYI; Eukaryota.
DR   GeneTree; ENSGT00940000162235; -.
DR   HOGENOM; CLU_803998_0_0_1; -.
DR   InParanoid; A7E371; -.
DR   OMA; FSDCGHH; -.
DR   OrthoDB; 1306595at2759; -.
DR   TreeFam; TF350402; -.
DR   Proteomes; UP000009136; Chromosome 19.
DR   Bgee; ENSBTAG00000017268; Expressed in spermatid and 105 other tissues.
DR   ExpressionAtlas; A7E371; baseline.
DR   GO; GO:0004623; F:phospholipase A2 activity; IEA:InterPro.
DR   GO; GO:0050482; P:arachidonic acid secretion; IEA:InterPro.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:InterPro.
DR   Gene3D; 1.20.90.10; -; 1.
DR   InterPro; IPR016090; PLipase_A2_dom.
DR   InterPro; IPR036444; PLipase_A2_dom_sf.
DR   Pfam; PF05826; Phospholip_A2_2; 1.
DR   SUPFAM; SSF48619; SSF48619; 1.
PE   2: Evidence at transcript level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..376
FT                   /note="Protein PROCA1"
FT                   /id="PRO_0000337249"
FT   REGION          180..376
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        250..267
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        304..349
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         319
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V7B4"
FT   MOD_RES         329
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V7B4"
FT   MOD_RES         330
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V7B4"
FT   MOD_RES         367
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V7B4"
FT   MOD_RES         376
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V7B4"
SQ   SEQUENCE   376 AA;  42242 MW;  61226D0A3BD65B98 CRC64;
     MWVRTTLRIE RWTKEKTEDD TSSWDESSTD INRLPSWGRG HLLASVESST DASTLSSEGE
     FKNTDRCCWK HKCAGHIVRP FSPDCVHHDV HLHSLSHCDC DSRLKDCSEK TNSSSGDVGP
     TCSRDVDSTC FDIIQSPCFE LIPEEECVER FWYGWCKSYR PVSVAVIHHP IHHECGADDL
     NQEEEEEEEE ESKPPIPTQV GPTPTDSPTD TGMSMITGAP DSAAPITIWR SESPTGKSQG
     NRVIKKIKKK KEKDKEEETD EKEKAKVKKK VKKGKLMKKK SPVKSESPPD LSRSLSPREL
     ARMSESSPDS RQDLESEDSY NDPGREEPSS EDIVESSSPR KREKNGVQVK KPGLKTSPVK
     KINKRRSPPA SNPNLS