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PRCA1_MOUSE
ID   PRCA1_MOUSE             Reviewed;         307 AA.
AC   B0QZF7;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=Protein PROCA1;
GN   Name=Proca1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=C57BL/6J;
RX   PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA   Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA   Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA   Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA   Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA   Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA   Eichler E.E., Ponting C.P.;
RT   "Lineage-specific biology revealed by a finished genome assembly of the
RT   mouse.";
RL   PLoS Biol. 7:E1000112-E1000112(2009).
CC   -!- SIMILARITY: Belongs to the PROCA1 family. {ECO:0000305}.
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DR   EMBL; AL591070; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS88201.1; -.
DR   RefSeq; XP_006533026.1; XM_006532963.3.
DR   AlphaFoldDB; B0QZF7; -.
DR   STRING; 10090.ENSMUSP00000086022; -.
DR   iPTMnet; B0QZF7; -.
DR   PhosphoSitePlus; B0QZF7; -.
DR   PaxDb; B0QZF7; -.
DR   PRIDE; B0QZF7; -.
DR   ProteomicsDB; 289398; -.
DR   Antibodypedia; 14279; 78 antibodies from 14 providers.
DR   Ensembl; ENSMUST00000108317; ENSMUSP00000103953; ENSMUSG00000044122.
DR   UCSC; uc007kin.1; mouse.
DR   MGI; MGI:1918274; Proca1.
DR   VEuPathDB; HostDB:ENSMUSG00000044122; -.
DR   eggNOG; ENOG502QTYI; Eukaryota.
DR   GeneTree; ENSGT00940000162235; -.
DR   HOGENOM; CLU_803998_0_0_1; -.
DR   InParanoid; B0QZF7; -.
DR   OMA; FSDCGHH; -.
DR   OrthoDB; 1306595at2759; -.
DR   BioGRID-ORCS; 216974; 1 hit in 72 CRISPR screens.
DR   ChiTaRS; Proca1; mouse.
DR   PRO; PR:B0QZF7; -.
DR   Proteomes; UP000000589; Chromosome 11.
DR   RNAct; B0QZF7; protein.
DR   Bgee; ENSMUSG00000044122; Expressed in seminiferous tubule of testis and 135 other tissues.
DR   ExpressionAtlas; B0QZF7; baseline and differential.
DR   Genevisible; B0QZF7; MM.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   GO; GO:0030332; F:cyclin binding; ISO:MGI.
DR   GO; GO:0004623; F:phospholipase A2 activity; IEA:InterPro.
DR   GO; GO:0050482; P:arachidonic acid secretion; IEA:InterPro.
DR   GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; ISS:UniProtKB.
DR   GO; GO:0035694; P:mitochondrial protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:InterPro.
DR   Gene3D; 1.20.90.10; -; 1.
DR   InterPro; IPR036444; PLipase_A2_dom_sf.
PE   3: Inferred from homology;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..307
FT                   /note="Protein PROCA1"
FT                   /id="PRO_0000336064"
FT   REGION          134..155
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          183..307
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        134..154
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        183..202
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        218..244
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        249..287
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         220
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V7B4"
FT   MOD_RES         250
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V7B4"
FT   MOD_RES         259
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V7B4"
FT   MOD_RES         260
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V7B4"
FT   MOD_RES         298
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V7B4"
FT   MOD_RES         307
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q4V7B4"
SQ   SEQUENCE   307 AA;  34900 MW;  2D6EC64787493840 CRC64;
     MWVRTTITVK RWTEERSGRK IERTERTDIT RLPSWKRGYP ASVDSSSDLF SFSEGENKET
     DRRCWKHQHC PGHTIHPFSD CGHHNRCMHA VSQCDCESRC RSHRPVSVAI IYHPTHHMYM
     TDDDLEENWV SRKNHLSPSA RPPDPNTGSA TEVPDLSVPI TIWRSESPIE KCQESNVIKD
     IKRKEKEQDE EEMVDEKANL KKKAKGKLTK KKTPVKSESS PADLSQSVRG PVRTPESSPE
     SPGGLESEYS CERGKERPSS EDVVESLSPR KKEKTSSGQA KKNGTKKETQ KTSKRKKSSP
     VPNPNLS
 
 
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