ID   PRCA1_RAT               Reviewed;         311 AA.
AC   Q4V7B4;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2005, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Protein PROCA1;
GN   Name=Proca1;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-224; SER-256; SER-265;
RP   SER-266; SER-302 AND SER-311, AND IDENTIFICATION BY MASS SPECTROMETRY
RP   [LARGE SCALE ANALYSIS].
RX   PubMed=22673903; DOI=10.1038/ncomms1871;
RA   Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C.,
RA   Olsen J.V.;
RT   "Quantitative maps of protein phosphorylation sites across 14 different rat
RT   organs and tissues.";
RL   Nat. Commun. 3:876-876(2012).
CC   -!- SIMILARITY: Belongs to the PROCA1 family. {ECO:0000305}.
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DR   EMBL; BC098036; AAH98036.1; -; mRNA.
DR   RefSeq; NP_001020929.1; NM_001025758.1.
DR   AlphaFoldDB; Q4V7B4; -.
DR   STRING; 10116.ENSRNOP00000031483; -.
DR   iPTMnet; Q4V7B4; -.
DR   PhosphoSitePlus; Q4V7B4; -.
DR   PaxDb; Q4V7B4; -.
DR   PRIDE; Q4V7B4; -.
DR   Ensembl; ENSRNOT00000037048; ENSRNOP00000031483; ENSRNOG00000023381.
DR   GeneID; 497959; -.
DR   KEGG; rno:497959; -.
DR   CTD; 147011; -.
DR   RGD; 1561727; Proca1.
DR   eggNOG; ENOG502QTYI; Eukaryota.
DR   GeneTree; ENSGT00940000162235; -.
DR   HOGENOM; CLU_803998_0_0_1; -.
DR   InParanoid; Q4V7B4; -.
DR   OMA; FSDCGHH; -.
DR   OrthoDB; 1306595at2759; -.
DR   PhylomeDB; Q4V7B4; -.
DR   TreeFam; TF350402; -.
DR   PRO; PR:Q4V7B4; -.
DR   Proteomes; UP000002494; Chromosome 10.
DR   Bgee; ENSRNOG00000023381; Expressed in testis and 19 other tissues.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   GO; GO:0030332; F:cyclin binding; ISO:RGD.
DR   GO; GO:0004623; F:phospholipase A2 activity; IEA:InterPro.
DR   GO; GO:0050482; P:arachidonic acid secretion; IEA:InterPro.
DR   GO; GO:0006123; P:mitochondrial electron transport, cytochrome c to oxygen; ISS:UniProtKB.
DR   GO; GO:0035694; P:mitochondrial protein catabolic process; ISS:UniProtKB.
DR   GO; GO:0007005; P:mitochondrion organization; ISS:UniProtKB.
DR   GO; GO:0006644; P:phospholipid metabolic process; IEA:InterPro.
DR   Gene3D; 1.20.90.10; -; 1.
DR   InterPro; IPR016090; PLipase_A2_dom.
DR   InterPro; IPR036444; PLipase_A2_dom_sf.
DR   Pfam; PF05826; Phospholip_A2_2; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..311
FT                   /note="Protein PROCA1"
FT                   /id="PRO_0000336065"
FT   REGION          139..159
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          184..311
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        187..206
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        222..240
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        241..284
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         224
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         256
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         265
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         266
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         302
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
FT   MOD_RES         311
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:22673903"
SQ   SEQUENCE   311 AA;  35333 MW;  367C0EE5527D5A11 CRC64;
     MWVRTTVTIR RWSEEKSGCN HERYPRTDIT RLPSWKRGYP ASVESSSDMS SFSEGENKET
     ERCCWKHQQC PVHIIHSFSD CGHHNRCMHA VSHCNCESRC QSYRPISVAI FHHPTHHMYM
     TDDLNDLEAN QLAITNNLCS TDRPTDPNSV ESTTGAPDLS APITIWRSAS PIDKCQEGKV
     IKNIKKKKKE KDKEEMMVDE KPKLKKKAKG KLIKKKSPMK SESSPADLSH SISPRELVRT
     SESSPDSREG LESEDSYERG KERPSSEDIV ESSPKKKEKC SAQAKKNATK NLQTRKTSKR
     KSPPVPNPNL S