PRE3_STAES
ID PRE3_STAES Reviewed; 413 AA.
AC Q8CUG0;
DT 07-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 76.
DE RecName: Full=Plasmid recombination enzyme type 3;
DE AltName: Full=Mobilization protein;
DE AltName: Full=Plasmid recombinase;
GN OrderedLocusNames=SE_p102;
OS Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200).
OG Plasmid pSE-12228-01.
OC Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=176280;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 12228 / FDA PCI 1200;
RX PubMed=12950922; DOI=10.1046/j.1365-2958.2003.03671.x;
RA Zhang Y.-Q., Ren S.-X., Li H.-L., Wang Y.-X., Fu G., Yang J., Qin Z.-Q.,
RA Miao Y.-G., Wang W.-Y., Chen R.-S., Shen Y., Chen Z., Yuan Z.-H.,
RA Zhao G.-P., Qu D., Danchin A., Wen Y.-M.;
RT "Genome-based analysis of virulence genes in a non-biofilm-forming
RT Staphylococcus epidermidis strain (ATCC 12228).";
RL Mol. Microbiol. 49:1577-1593(2003).
CC -!- FUNCTION: The interaction of the RSA site and the PRE protein may not
CC only serves a function in plasmid maintenance, but may also contributes
CC to the distribution of small antibiotic resistance plasmids among Gram-
CC positive bacteria. {ECO:0000250}.
CC -!- MISCELLANEOUS: Contains conserved positively charged amino acids
CC probably involved in the binding of the pre protein to the RSA site.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the plasmid mobilization pre family.
CC {ECO:0000305}.
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DR EMBL; AE015930; AAO06149.1; -; Genomic_DNA.
DR RefSeq; NP_863257.1; NC_005008.1.
DR RefSeq; WP_000122374.1; NZ_WBME01000087.1.
DR AlphaFoldDB; Q8CUG0; -.
DR SMR; Q8CUG0; -.
DR EnsemblBacteria; AAO06149; AAO06149; SE_p102.
DR GeneID; 50019750; -.
DR GeneID; 61682014; -.
DR GeneID; 66909090; -.
DR KEGG; sep:SE_p102; -.
DR PATRIC; fig|176280.10.peg.2432; -.
DR HOGENOM; CLU_035698_0_0_9; -.
DR OMA; VEDYFER; -.
DR Proteomes; UP000001411; Plasmid pSE-12228-01.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR InterPro; IPR001668; Mob_Pre.
DR Pfam; PF01076; Mob_Pre; 1.
PE 3: Inferred from homology;
KW DNA-binding; Plasmid.
FT CHAIN 1..413
FT /note="Plasmid recombination enzyme type 3"
FT /id="PRO_0000224928"
FT REGION 179..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 374..413
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 179..193
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..218
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 45
FT /ligand="DNA"
FT /ligand_id="ChEBI:CHEBI:16991"
FT /evidence="ECO:0000255"
FT BINDING 115
FT /ligand="DNA"
FT /ligand_id="ChEBI:CHEBI:16991"
FT /evidence="ECO:0000255"
SQ SEQUENCE 413 AA; 48526 MW; 8F16FF8D82998659 CRC64;
MSYSIVRVSK VKSGTNTTGI QKHVQRENNN YENEDIDHSK TYLNYDLVNA NKQNFNNLID
EKIEQNYTGK RKIRTDAIKH IDGLITSDND FFDNQTPEDT KQFFEYAKEF LEQEYGKDNL
LYATVHMDEK TPHMHYGVVP ITDDGRLSAK EVVGNKKALT AFQDRFNEHV KQRGYDLERG
QSRQVTNAKH EQISQYKQKT EYHKQEYERE SQKTDHIKQK NDKLMQEYQK SLNTLKKPIN
VPYEQETEKV GGLFSKEIQE TGNVVISQKD FNEFQKQIKA AQDISEDYEY IKSGRALDDK
DKEIREKDDL LNKAVERIEN ADDNFNQLYE NAKPLKENIE IALKLLKILL KELERVLGRN
TFAERVNKLT EDEPKLNGLA GNLDKKMNPE LYSEQEQQQE QQKNQKRDRG MHL
