ID   PRE_BACSP               Reviewed;         415 AA.
AC   P13015;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1990, sequence version 1.
DT   25-MAY-2022, entry version 50.
DE   RecName: Full=Plasmid recombination enzyme;
GN   Name=pre;
OS   Bacillus sp.
OG   Plasmid pTB913.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1409;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2677995; DOI=10.1093/nar/17.18.7283;
RA   van der Lelie D., Bron S., Venema G., Oskam L.;
RT   "Similarity of minus origins of replication and flanking open reading
RT   frames of plasmids pUB110, pTB913 and pMV158.";
RL   Nucleic Acids Res. 17:7283-7294(1989).
CC   -!- FUNCTION: The interaction of the RSA site and the pre protein may not
CC       only serve a function in plasmid maintenance, but also contribute to
CC       the distribution of small antibiotic resistance plasmids among Gram-
CC       positive bacteria.
CC   -!- MISCELLANEOUS: Contains conserved positively charged amino acids
CC       probably involved in the binding of the pre protein to the RSA site.
CC   -!- SIMILARITY: Belongs to the plasmid mobilization pre family.
CC       {ECO:0000305}.
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DR   EMBL; M63891; AAA98307.1; -; Genomic_DNA.
DR   EMBL; X15670; CAA33717.1; -; Genomic_DNA.
DR   PIR; S05987; S05987.
DR   AlphaFoldDB; P13015; -.
DR   SMR; P13015; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:InterPro.
DR   InterPro; IPR001668; Mob_Pre.
DR   Pfam; PF01076; Mob_Pre; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Plasmid.
FT   CHAIN           1..415
FT                   /note="Plasmid recombination enzyme"
FT                   /id="PRO_0000068416"
FT   REGION          20..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   415 AA;  48821 MW;  D4C3585F2761459B CRC64;
     MSFAVVRMQK MKSYDLKGIQ FHNQRERESK TNPDIDKERS HENYDLVNDE PIDYNERVKE
     IIESQKVGTR KTRKDAVLVN ELIVTSDRHF FERLDPDEQK RFFEESYKLF ADRYGKQNIA
     YATVHVDEKT PHMHLGVVPM RDGKLQGKNV FNRQELLWLQ DKFPEHMQKL GFDLQRGEKG
     SDREHIETSK FKKQTLEKEI DLLENELKNK KSELAILSEE VSGEFKIPVK REKKSVEVPT
     GKRNLLGIEQ KKTVMKSTGN VILKDEVFQD LKQKVKAGAV LQTRVDQLLN TDYAKENQSL
     KKEVKELRST NKSLSEENGR LKSTVEHLTN EIESLYVLTK DFLKARTNDL ESFKELFGVF
     VGKVKEKAPR GLFVRQHERS EEKKNTFSLQ DVLQRDRELR EQRKAKRKKS HDLER