PRGI_SALTY
ID PRGI_SALTY Reviewed; 80 AA.
AC P41784;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Protein PrgI;
GN Name=prgI; OrderedLocusNames=STM2873;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 14028s / SGSG 2262;
RX PubMed=7476203; DOI=10.1111/j.1365-2958.1995.mmi_17010169.x;
RA Pegues D.A., Hantman M.J., Behlau I., Miller S.I.;
RT "PhoP/PhoQ transcriptional repression of Salmonella typhimurium invasion
RT genes: evidence for a role in protein secretion.";
RL Mol. Microbiol. 17:169-181(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
CC -!- FUNCTION: Required for invasion of epithelial cells.
CC -!- INTERACTION:
CC P41784; P41784: prgI; NbExp=8; IntAct=EBI-15861111, EBI-15861111;
CC -!- SIMILARITY: Belongs to the MxiH/PrgI/YscF family. {ECO:0000305}.
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DR EMBL; U21676; AAB60189.1; -; Genomic_DNA.
DR EMBL; AE006468; AAL21753.1; -; Genomic_DNA.
DR PIR; S69784; S69784.
DR RefSeq; NP_461794.1; NC_003197.2.
DR RefSeq; WP_000235228.1; NC_003197.2.
DR PDB; 2JOW; NMR; -; A=1-75.
DR PDB; 2KV7; NMR; -; A=1-80.
DR PDB; 2LPZ; NMR; -; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z/a/b/c=1-80.
DR PDB; 2MEX; NMR; -; A/B/C/D=1-80.
DR PDB; 2X9C; X-ray; 2.45 A; A/B=1-80.
DR PDB; 3ZQB; X-ray; 2.40 A; A/B=1-80.
DR PDB; 3ZQE; X-ray; 2.19 A; A/B=1-80.
DR PDB; 6DWB; EM; 3.30 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W/X/Y/Z/a/b/c/d=1-80.
DR PDB; 6OFE; EM; 3.61 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T=1-80.
DR PDB; 6OFF; EM; 3.20 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R=1-80.
DR PDB; 6OFG; EM; 2.90 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R=1-80.
DR PDB; 6OFH; EM; 3.70 A; D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V=1-80.
DR PDB; 6PEP; EM; 3.80 A; AS/AT/AU/AV/AW/AX/AY/AZ/BA/BB/BC/BD/BE=1-80.
DR PDB; 6Q15; EM; 5.15 A; AS/AT/AU/AV/AW/AX/AY/AZ/BA/BB/BC/BD/BE/BF/BG/BH/BI/BJ/BK/BL/BM/BN/BO/BP/BQ/BR/BS/BT/BU/BV=1-80.
DR PDB; 6Q16; EM; 4.10 A; AS/AT/AU/AV/AW/AX/AY/AZ/BA/BB/BC/BD/BE=1-80.
DR PDB; 6ZNH; EM; 3.60 A; A/B/C/D/E/F/G/H/I/J/K/L/M/N/O/P/Q/R/S/T/U/V/W=1-80.
DR PDB; 7AGX; EM; 3.60 A; 2A/2B/2C/2D/2E/2F/2G/2H/2I/2J/2K/2L/2M/2N/2O/2P/2Q=1-80.
DR PDB; 7AH9; EM; 3.30 A; 2A/2B/2C/2D/2E/2F/2G/2H/2I/2J/2K/2L/2M/2N/2O/2P/2Q/2R/2S/2T/2U/2V/2W/2X/2Y/2Z/3A/3B/3C/3D=1-80.
DR PDB; 7AHI; EM; 3.30 A; 2A/2B/2C/2D/2E/2F/2G/2H/2I/2J/2K/2L/2M/2N/2O/2P/2Q/2R/2S/2T/2U/2V/2W/2X/2Y/2Z/3A/3B/3C/3D=1-80.
DR PDB; 7RYE; EM; 3.90 A; A/B/C/D/E/G/H/I/J/K/L/M/N/P/Q/S/T/U/W=1-80.
DR PDBsum; 2JOW; -.
DR PDBsum; 2KV7; -.
DR PDBsum; 2LPZ; -.
DR PDBsum; 2MEX; -.
DR PDBsum; 2X9C; -.
DR PDBsum; 3ZQB; -.
DR PDBsum; 3ZQE; -.
DR PDBsum; 6DWB; -.
DR PDBsum; 6OFE; -.
DR PDBsum; 6OFF; -.
DR PDBsum; 6OFG; -.
DR PDBsum; 6OFH; -.
DR PDBsum; 6PEP; -.
DR PDBsum; 6Q15; -.
DR PDBsum; 6Q16; -.
DR PDBsum; 6ZNH; -.
DR PDBsum; 7AGX; -.
DR PDBsum; 7AH9; -.
DR PDBsum; 7AHI; -.
DR PDBsum; 7RYE; -.
DR AlphaFoldDB; P41784; -.
DR BMRB; P41784; -.
DR SMR; P41784; -.
DR DIP; DIP-59025N; -.
DR IntAct; P41784; 2.
DR STRING; 99287.STM2873; -.
DR TCDB; 3.A.6.1.3; the type iii (virulence-related) secretory pathway (iiisp) family.
DR PaxDb; P41784; -.
DR EnsemblBacteria; AAL21753; AAL21753; STM2873.
DR GeneID; 1254396; -.
DR KEGG; stm:STM2873; -.
DR PATRIC; fig|99287.12.peg.3029; -.
DR HOGENOM; CLU_171855_1_1_6; -.
DR OMA; PNKDWTL; -.
DR BioCyc; SENT99287:STM2873-MON; -.
DR EvolutionaryTrace; P41784; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0030257; C:type III protein secretion system complex; IEA:InterPro.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR GO; GO:0030254; P:protein secretion by the type III secretion system; IEA:InterPro.
DR InterPro; IPR021123; T3SS_needle-like.
DR InterPro; IPR037203; T3SS_needle-like_sf.
DR InterPro; IPR011841; T3SS_needle_YscF.
DR Pfam; PF09392; T3SS_needle_F; 1.
DR SUPFAM; SSF140129; SSF140129; 1.
DR TIGRFAMs; TIGR02105; III_needle; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Protein transport; Reference proteome; Transport; Virulence.
FT CHAIN 1..80
FT /note="Protein PrgI"
FT /id="PRO_0000058572"
FT HELIX 5..7
FT /evidence="ECO:0007829|PDB:2JOW"
FT HELIX 9..36
FT /evidence="ECO:0007829|PDB:3ZQE"
FT STRAND 37..39
FT /evidence="ECO:0007829|PDB:2KV7"
FT HELIX 41..62
FT /evidence="ECO:0007829|PDB:3ZQE"
FT HELIX 64..75
FT /evidence="ECO:0007829|PDB:3ZQE"
FT HELIX 77..79
FT /evidence="ECO:0007829|PDB:6OFG"
SQ SEQUENCE 80 AA; 8857 MW; ED1F8967877585F8 CRC64;
MATPWSGYLD DVSAKFDTGV DNLQTQVTEA LDKLAAKPSD PALLAAYQSK LSEYNLYRNA
QSNTVKVFKD IDAAIIQNFR
