PRH1_MOUSE
ID PRH1_MOUSE Reviewed; 261 AA.
AC P05142; Q62107;
DT 13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 2.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Proline-rich protein HaeIII subfamily 1;
DE AltName: Full=Proline-rich protein MP-2;
DE Flags: Precursor;
GN Name=Prh1; Synonyms=Prp;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2999141; DOI=10.1016/s0021-9258(17)36338-x;
RA Ann D.K., Carlson D.M.;
RT "The structure and organization of a proline-rich protein gene of a mouse
RT multigene family.";
RL J. Biol. Chem. 260:15863-15872(1985).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 1-227.
RX PubMed=3840480; DOI=10.1016/s0021-9258(17)38745-8;
RA Clements S., Mehansho H., Carlson D.M.;
RT "Novel multigene families encoding highly repetitive peptide sequences.
RT Sequence analyses of rat and mouse proline-rich protein cDNAs.";
RL J. Biol. Chem. 260:13471-13477(1985).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
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DR EMBL; M12099; AAA40004.1; -; Genomic_DNA.
DR EMBL; M11902; AAA40003.1; -; mRNA.
DR PIR; A24264; A24264.
DR PIR; C29149; C29149.
DR AlphaFoldDB; P05142; -.
DR PaxDb; P05142; -.
DR PRIDE; P05142; -.
DR MGI; MGI:97773; Prh1.
DR PRO; PR:P05142; -.
DR Proteomes; UP000000589; Unplaced.
DR RNAct; P05142; protein.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR026086; Pro-rich.
DR PANTHER; PTHR23203; PTHR23203; 2.
DR SMART; SM01412; Pro-rich; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Repeat; Secreted; Signal.
FT SIGNAL 1..15
FT /evidence="ECO:0000255"
FT CHAIN 16..261
FT /note="Proline-rich protein HaeIII subfamily 1"
FT /id="PRO_0000022133"
FT REGION 15..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..241
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 18
FT /note="G -> Q (in Ref. 2; AAA40003)"
FT /evidence="ECO:0000305"
FT CONFLICT 23
FT /note="N -> L (in Ref. 1; AAA40004)"
FT /evidence="ECO:0000305"
FT CONFLICT 102
FT /note="Q -> P (in Ref. 1; AAA40004)"
FT /evidence="ECO:0000305"
FT CONFLICT 116
FT /note="Q -> P (in Ref. 2; AAA40003)"
FT /evidence="ECO:0000305"
FT CONFLICT 180
FT /note="P -> T (in Ref. 1; AAA40004)"
FT /evidence="ECO:0000305"
FT CONFLICT 200
FT /note="R -> Q (in Ref. 1; AAA40004)"
FT /evidence="ECO:0000305"
FT CONFLICT 213
FT /note="P -> L (in Ref. 2; AAA40003)"
FT /evidence="ECO:0000305"
FT CONFLICT 223
FT /note="G -> A (in Ref. 2; AAA40003)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 261 AA; 26090 MW; 538900A6947AF475 CRC64;
MLVVLFTVAL LALSSAQGPR EENQNQIQIP NQRPPPSGFQ PRPPVNGSQQ GPPPPGGPQP
RPPQGPPPPG GPQPRPPQGP PPPGGPQPRP PQGPPPPGGP QQRPPQGPPP PGGPQQRPPQ
GPPPPGGPQP RPPQGPPPPG GPQLRPPQGP PPPAGPQPRP PQGPPPPAGP QPRPPQGPPP
TGPQPRPTQG PPPTGGPQQR PPQGPPPPGG PQPRPPQGPP PPGGPQPSPT QGPPPTGGPQ
QTPPLAGNTQ GPPQGRPQGP R
