ID   PRIM_ASFM2              Reviewed;        1102 AA.
AC   P0CA12;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=Putative helicase/primase complex protein;
DE            Short=pF1055L;
GN   OrderedLocusNames=Mal-055;
OS   African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10500;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in DNA replication.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus F1055L family. {ECO:0000305}.
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DR   EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Proteomes; UP000000860; Genome.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:InterPro.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR003450; Replication_origin-bd.
DR   Pfam; PF02399; Herpes_ori_bp; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
PE   3: Inferred from homology;
KW   DNA replication; Early protein.
FT   CHAIN           1..1102
FT                   /note="Putative helicase/primase complex protein"
FT                   /id="PRO_0000373469"
FT   REGION          1031..1057
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1082..1102
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1033..1057
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1102 AA;  129256 MW;  4B06FAA67F304C60 CRC64;
     MQETFKFLRS NSQGEAVEDK YSLETLKNHF VIRDEYNNLF RVFSGRDDFW KWEAAQPFEQ
     KCFHEVVFGF LPQRLKFDID FPVNKSYSND NVDDNVDDNV YNILDMIINV IMDVFYETYS
     LPYNINLTRE QILLTDSIGL NKKRELKYSF HIILYTYSVL NNNEAKAFTS KVLENLPKHI
     YPFVDPQVNK SIQNFRIIGS HKKGSMRVKM FNEELADVFE TSMTTKKSDT LISTPFETTC
     LPCILTNVKE TTSSSCDSIQ QSELEEVLKF AGTLCKNHCF LRVYKNLVLF KRTSPSYCEI
     CKRMHDKDNT LILRVTGNKV YQHCRHDNKH SLLMGSLSGT NNFVETYVEQ VMSKSIEVHE
     SILFEELPDT QKHIYDESSM REYERVPTLV VKAQMKIGKT IQLRNYLQKY YGNDSISKQQ
     TIRFVTFRQI FSKNIQTRLP NFTLYSEVTG DLDSYERVII QVESLFRLTS TAEPVDLLIL
     DEVESIFNQF NSGLHKYFAP SFAIFMWMLE TANHVICLDA NLGNRTYNIL QRFRGDVPIF
     FHWNQYQKAQ NDMYYFTSSR EIWLNNLLKD LLEDKKIVIP TNSLMEARLL QTFIQKKFPE
     KKIGFYSSKS SAHERESHFN NVSYYWGLID ILIYTPTISA GVSYEDKRFD VLYGFFNNMS
     CDVETCCQML GRVRELKSKC YKICLQGKQN YFPETIEDIE MFTLQKRDTL FQTISNHQLS
     FTYCKETGRP IYYKTPYYHL WLETMRIQHL SKNHFITRFI NQVADTGAKV FILTGEKLET
     VKQYTSIKME IKHQDYVNVA SAETIDANKA LQIKQNLKEG ITVDQRDLFA YEKYKLLEFY
     AWHGNKITPK FVEQYNSFMT KQNYTGRVQI SRGKTVYESL TMLQTQELNF HQWAMQHAEH
     HDLQFNYSFQ SHMYAIMLLT KCGFKCVQDP NILTNEQLMT KLVDEFVQYD LSAVSFEFKL
     KKPNKMDPQT ILKFINKVLG LRYGLKIHHN KGNYYIKNTK AGSLIPFVRQ PIKQSPCVVS
     NLLPITESSS TKEEISSTKE ETYSTKEETY STKEETCSIK EEISPIKEET CSIKEEISPI
     KEETCSIKEE TSSIKEETFT ET