ID   PRM10_CANGA             Reviewed;         786 AA.
AC   Q6FT92;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Pheromone-regulated membrane protein 10;
GN   OrderedLocusNames=CAGL0G04433g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ThrE exporter (TC 2.A.79) family.
CC       {ECO:0000305}.
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DR   EMBL; CR380953; CAG59479.1; -; Genomic_DNA.
DR   RefSeq; XP_446552.1; XM_446552.1.
DR   AlphaFoldDB; Q6FT92; -.
DR   STRING; 5478.XP_446552.1; -.
DR   EnsemblFungi; CAG59479; CAG59479; CAGL0G04433g.
DR   GeneID; 2888410; -.
DR   KEGG; cgr:CAGL0G04433g; -.
DR   CGD; CAL0129301; CAGL0G04433g.
DR   VEuPathDB; FungiDB:CAGL0G04433g; -.
DR   eggNOG; ENOG502QPMM; Eukaryota.
DR   HOGENOM; CLU_007078_1_1_1; -.
DR   InParanoid; Q6FT92; -.
DR   Proteomes; UP000002428; Chromosome G.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010619; ThrE.
DR   InterPro; IPR024528; ThrE_2.
DR   Pfam; PF06738; ThrE; 1.
DR   Pfam; PF12821; ThrE_2; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..786
FT                   /note="Pheromone-regulated membrane protein 10"
FT                   /id="PRO_0000409252"
FT   TRANSMEM        469..489
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        491..511
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        521..541
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        545..565
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        584..604
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        620..640
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        645..665
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        675..695
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        697..717
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        751..771
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..65
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          77..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..28
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        29..45
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        46..65
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   786 AA;  85391 MW;  92FA5C783810441E CRC64;
     MADSGDKDVS KSVRFDKESI ESKKRSSVDD SASSYSSSSS GQDRSEGKRN NVKFSTEDSD
     DEDGNLFSRM IKNLKSNGGA GLAPGLSKAN SNQEKTDLED NDNVVTGHSD DIPMEDFTSE
     AQNILQGHSN LTPAQIEALN GQGLSDIETT ASSTDLNFLA PAIDHFDDFD GDGEEENDGF
     VDTHGYVAPP TQVRGGVLGS LLKLYQEQDN ATIETSSMYS QSSYGESTAN LMSIDSGETE
     VPSEHKPKDH KNVFMRSGGK VAGLAMNAPG QIYGHGSKAA GHIYGHGRKG AGHIYNQGKK
     GAGHIYSQKN KLSSADLSTE GLKKSGHKAK KVAGKMPKLR KRMLAEAKIT VHIAELLQRQ
     RFILRMCKAL MLYGAPTHRL EEYMIMTSRV LEIDGQYLYL PGCMIVSFGD ATTRTSEVQL
     VRCTQGLNLW KLHQVHGVYK KVIHDQMGAD EGNIEIDRIL REKNLYPPWV CVFLYGFCSA
     MVTPYAFGGH WINLAITFFM GSCVGMMQFI LSEKSLMYSN VFEITASIVV SFCGRAFGSI
     PNSNICFGAI TQGSLALILP GYIILCGSLE LQSRSLVAGS VRMFYAIIYS LFLGFGITLG
     AALFGWMYKG ATNEISCGYP ISPWFRFLFV PAFTIGISLI NQANWTQLPA MVFISCTGYV
     VTYWSGKHFQ NSTEFTAALA SFVIGILGNL YSRIWQGLAV SAMLPAIFVQ VPSGIASQNS
     LLSGLQSANQ IVGRNGTNAV QTVDLSNSMS FGITMIEVSI GISVGLFAST LCVYPFGKKK
     TGLFSL