PRM10_DEBHA
ID PRM10_DEBHA Reviewed; 1008 AA.
AC Q6BVE3;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 04-NOV-2008, sequence version 2.
DT 03-AUG-2022, entry version 66.
DE RecName: Full=Pheromone-regulated membrane protein 10;
GN OrderedLocusNames=DEHA2C03278g;
OS Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990
OS / NBRC 0083 / IGC 2968) (Yeast) (Torulaspora hansenii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Debaryomyces.
OX NCBI_TaxID=284592;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the ThrE exporter (TC 2.A.79) family.
CC {ECO:0000305}.
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DR EMBL; CR382135; CAG85871.2; -; Genomic_DNA.
DR RefSeq; XP_457826.2; XM_457826.1.
DR AlphaFoldDB; Q6BVE3; -.
DR STRING; 4959.XP_457826.2; -.
DR EnsemblFungi; CAG85871; CAG85871; DEHA2C03278g.
DR GeneID; 2900144; -.
DR KEGG; dha:DEHA2C03278g; -.
DR VEuPathDB; FungiDB:DEHA2C03278g; -.
DR eggNOG; ENOG502QPMM; Eukaryota.
DR HOGENOM; CLU_007078_1_0_1; -.
DR InParanoid; Q6BVE3; -.
DR OMA; FVYFPGT; -.
DR OrthoDB; 944115at2759; -.
DR Proteomes; UP000000599; Chromosome C.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR010619; ThrE.
DR InterPro; IPR024528; ThrE_2.
DR Pfam; PF06738; ThrE; 1.
DR Pfam; PF12821; ThrE_2; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..1008
FT /note="Pheromone-regulated membrane protein 10"
FT /id="PRO_0000409253"
FT TRANSMEM 683..703
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 707..727
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 736..756
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 762..782
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 800..820
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 838..858
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 866..886
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 892..912
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 917..937
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 978..998
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 342..384
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 477..506
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..52
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..115
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 119..159
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..182
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 183..227
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 344..368
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 369..384
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1008 AA; 110908 MW; DAA17005B5A18D27 CRC64;
MSQSFPRNDT SSSSEDETDN YRSHIQIPSL DLANYRKQQK STSKTNLAKA GKKLKNNKSV
RFPDSYSPRD TIISNASTTN NSSSDSELEQ DMVTGENSNL PNFNFSANQV HSPEYANEDD
ANDDSGEEED TFEPPADFYA SEGSDEDMEA DNEGDNVEDK EEVVNEKEEI ADDLHSKSSK
TSRESKSFNA GTKNSRRSLN SLQRNETDVT DQLKRTTSTT SSSKRSNSDK RTGFKDILRK
FALVDQQYPE APSNRESEDL GEPQPSRSDT FLGNVLSMAG ESGGLVPGAT HFSREKTIDE
EEEVGFEDED SDLIEMKKLD FAQLSNEAQN LISTHVPDLA NKLPEGTSSD QQLDYSDTSA
SNLIKNDEET GNEATKKDDE FYTPNPDYFI RGDINNENDA DDYLMLDEHM DDIAPPKRVQ
AGVLSSLLKL YQNPQEQQSS SSLTSKSTYG GNTLADDSNY SYSDPKAAST LDFTKLKNDF
KNGPKRMANK IPGRKHGAQK QDTQDESAQK YYDEDGNEIA APNLPSFHNA KPKAPKKIAA
AGKVPSKVHK KLKEHKRQQD QQLRITVHIA DILHRQRFIM RMCKALMMFG APTHRLEEYM
TLTSRVLEID GQFVYFPGCM IVSFGDASTR TSEVHLVRCA QGLNLSKLSD THRIYKGVIH
DILPVDEAST QLEELLKKKN RYSPWLCVFL YGLGSSMVCP FAFNGGWYDV PIAFGVGLCV
GYLQFFVSSK SNLYSSVFEV TASIVVTFIA RAIGSIHDGE YFCFSAIAQG SLALILPGYI
ILTGSLELQS RNIVAGSVRM FYAIIYSLFL GFGITLGASL YGWVDSNAIS TTKCKNSIKQ
DEFKILFVPL FSACLGLINQ ARWRQLPIMI VIACAGYVGT FFAGKHKQFS EVTEFTACIG
AFIVGILGNL YSRIGKGMAV AAMLPAIFVQ VPSGIASQST LLAGVESADK LTSSNSTTTD
TSTASDSAGS LAFGATMVKV SIGISVGLFA SALFVYPFGK KKTGLFSL
