PRM10_YARLI
ID PRM10_YARLI Reviewed; 1219 AA.
AC Q6C4Q0;
DT 31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 67.
DE RecName: Full=Pheromone-regulated membrane protein 10;
GN OrderedLocusNames=YALI0E24651g;
OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Dipodascaceae; Yarrowia.
OX NCBI_TaxID=284591;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CLIB 122 / E 150;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the ThrE exporter (TC 2.A.79) family.
CC {ECO:0000305}.
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DR EMBL; CR382131; CAG79961.1; -; Genomic_DNA.
DR RefSeq; XP_504362.1; XM_504362.1.
DR AlphaFoldDB; Q6C4Q0; -.
DR STRING; 4952.CAG79961; -.
DR EnsemblFungi; CAG79961; CAG79961; YALI0_E24651g.
DR GeneID; 2912656; -.
DR KEGG; yli:YALI0E24651g; -.
DR VEuPathDB; FungiDB:YALI0_E24651g; -.
DR HOGENOM; CLU_007078_1_0_1; -.
DR InParanoid; Q6C4Q0; -.
DR Proteomes; UP000001300; Chromosome E.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR010619; ThrE.
DR Pfam; PF06738; ThrE; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..1219
FT /note="Pheromone-regulated membrane protein 10"
FT /id="PRO_0000409256"
FT TRANSMEM 864..884
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 888..908
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 918..938
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 945..965
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 983..1003
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1021..1041
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1049..1069
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1075..1095
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1100..1120
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 1184..1204
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 303..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 503..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..21
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..44
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 99..157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 177..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 234..273
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 326..346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 391..422
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..484
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..639
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..672
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 695..713
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1219 AA; 133048 MW; 9A722B50C47578BC CRC64;
MMRTQSDEHV ATRSSSANKQ RQRVRFPKDN DPTTKRILYP ADENDDGHDD SDEKETSVVI
PTPSVVIVGP DGEEPASAPI STGSPGADTD DYFSTHPNKK KSTLKSPGTP TTYSPSVPAG
RARSATGVTT HTPPKGSSLS STTLMNTLLN SSGLGQYDTE SEEDDDEDEE VTFTARPRQP
AQPSNSEEAG PSEQPQFRID KVKSISLMRA RQSRAREAQE EETVASTDDD GVGNNDMFKI
DDDARSVSTD ESSDDESDAD RAARADAPLI ERERASAAHV DAFAQNSERG SNMAVGAAIM
GGLASFGSMS GGGMAPGAVD RSSESSQTLD DQRDQRDSHL ALRRENALGM HSHSAPGSED
HTPGDASGNA SAGNHDDGED SLAGHDINDI PLVALDRRLE DIKEKRAEDK EKRAEDNEKE
RQHHHHNHHH HHSSETGPNT GASSPFSEEE KDREAEEAEI LRDQARDLVN QHKHAVHTPD
AEDEDYDPFT APAVDYFSSI HIHDDDEDED NHGNFLTYDA ADGSVTPTHE DYVAPPKRFK
QGVLGALLKL YNEEEGNKST STLATTVGDG TSTGDVSPML YGSEPTTPGG TPIDHPTKSK
TKTTQKLGLK KKKKELLKII EDQRKEKEEN KKRPKWYDKS RSTSPSPGGT PAPHHHHHIP
GLHLHHHTKG HQRSHSEGYL DEMETAAGGG GDGGDKPPDR PRSLRSEALR PVKDIKKLNK
MAKNTGKNFK KRERELKRRR RQEVKITVHI AELLQRQRFI LRMCRALMLY GAPTHRLEEY
MKMTSRILEI DGQFLYIPGC MIVSFGDATT HTSEMQLVRC VQGVNLSKLQ DTHEIYKEVV
HDMIGVEEAS NRLDEILRSK NLYPPWLCVI FFACGTGVVS PYAFRGRWAD IPMCIILGSV
VGFFQIIVAP RSDLYNNVFE VSMSILISFL ARAIGTISSG GSHPFCFAAI AQGSLAIILP
GYIVLCGSLE LQSKNIVAGS IRMFYAVIYS MFLGFGITLG AVVYGWCDHN ATRQDKCPQQ
LDPLWRILFV PLYSFFIALV NQARITQLPS MLLISGAGYT VTYFVGANIP DPDNSSYLTS
AIGAFTIGIL GNLYSRLGHG LAFAAMLPGI FVQVPSGVAS QGSLVAAIAN SNRLIGNKNV
TTTIRETIVN SATSTVVTRV QTSLLTETST AAIEQATPGG AANLGFTMIQ VAIGITVGLF
AATLCVYPFG KKRSGLFTF
