ID   PRM10_YEAS7             Reviewed;         770 AA.
AC   A6ZQL9;
DT   31-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=Pheromone-regulated membrane protein 10;
GN   Name=PRM10; ORFNames=SCY_3180;
OS   Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=307796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=YJM789;
RX   PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA   Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA   Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA   Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA   Steinmetz L.M.;
RT   "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT   strain YJM789.";
RL   Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC   -!- SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
CC   -!- SIMILARITY: Belongs to the ThrE exporter (TC 2.A.79) family.
CC       {ECO:0000305}.
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DR   EMBL; AAFW02000044; EDN63271.1; -; Genomic_DNA.
DR   AlphaFoldDB; A6ZQL9; -.
DR   EnsemblFungi; EDN63271; EDN63271; SCY_3180.
DR   HOGENOM; CLU_007078_1_1_1; -.
DR   Proteomes; UP000007060; Unassembled WGS sequence.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR010619; ThrE.
DR   InterPro; IPR024528; ThrE_2.
DR   Pfam; PF06738; ThrE; 1.
DR   Pfam; PF12821; ThrE_2; 1.
PE   3: Inferred from homology;
KW   Membrane; Transmembrane; Transmembrane helix.
FT   CHAIN           1..770
FT                   /note="Pheromone-regulated membrane protein 10"
FT                   /id="PRO_0000409257"
FT   TRANSMEM        453..473
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        475..495
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        505..525
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        529..549
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        568..588
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        604..624
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        629..649
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        659..679
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        681..701
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        740..760
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          139..169
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..91
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..106
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        155..169
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   770 AA;  83961 MW;  869C43E5B4A0D6E9 CRC64;
     MDGRNERPTT PVSDFRVGSS EQSQAGVNLE DSSDYRTSNS AESKKGNLSG KSISDLGISN
     NDNKNVRFTA DTDALENDLS SRSTETSDNS KGTDGQGEED RPARHKRKPK VSFTHLRNNG
     KDGDDETFIK KIINNLTGNQ GGLVPGLAPI PSENENGKDD IEKNNRNEEI PLSDLADASK
     IVDVHEGDNK EKLEALKLES DVNCTSDGET LGSSSKNSFL APAVDHFDDY AENNSSDDNE
     GFIETSTYVP PPSQVKSGVL GSLLKLYQNE DQNSSSIFSD SQAVTTDDEG ISSTAGNKDV
     PVAKRSRLQN LKGKAKKGRM PRLKKRLKTE AKITVHIADI LQRHRFILRM CRALMMYGAP
     THRLEEYMVM TSRVLEIDGQ FLYLPGCMIV SFGDATTRTS EVQLVRCTQG LNLWKLHQVH
     AVYKRVVHDT LGADEGNALL DQILADTNLY PPWMCVLLYA FCSAMVTPYA FGGDWVNLAI
     SFFMGLCVGS LQFILSQKSY MYSNVFEISA SIVVSFCGRA FGSIPRSHIC FGAVTQGSLA
     LILPGYIILC GALELQSRSL VAGAVRMFYA IIYSLFLGFG ITLGSALFGW MYHNATNEIS
     CPQLISPWFR FLFVPAFTIS ISLLNQAHIS QLPVMVFISC TGYVVTYWAG KHFANSTEFT
     AALAAFVIGV LGNLYSRIWK GLAVSAMLPA IFVQVPSGIA SQNSLLSGLQ SANTIVNANE
     TITTSTSDPS SSMSFGMTMI QVCVGISVGL FASSLFVYPF GKKKTGLFSL