PRM1_ASPOR
ID PRM1_ASPOR Reviewed; 722 AA.
AC Q2UJS0;
DT 20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JAN-2006, sequence version 1.
DT 03-AUG-2022, entry version 74.
DE RecName: Full=Plasma membrane fusion protein prm1;
GN Name=prm1; ORFNames=AO090003001100;
OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus;
OC Aspergillus subgen. Circumdati.
OX NCBI_TaxID=510516;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 42149 / RIB 40;
RX PubMed=16372010; DOI=10.1038/nature04300;
RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., Kusumoto K.,
RA Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., Horiuchi H.,
RA Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., Galagan J.E.,
RA Nierman W.C., Yu J., Archer D.B., Bennett J.W., Bhatnagar D.,
RA Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., Hosoyama A.,
RA Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., Kato M., Kato Y.,
RA Kin T., Kokubun A., Maeda H., Maeyama N., Maruyama J., Nagasaki H.,
RA Nakajima T., Oda K., Okada K., Paulsen I., Sakamoto K., Sawano T.,
RA Takahashi M., Takase K., Terabayashi Y., Wortman J.R., Yamada O.,
RA Yamagata Y., Anazawa H., Hata Y., Koide Y., Komori T., Koyama Y.,
RA Minetoki T., Suharnan S., Tanaka A., Isono K., Kuhara S., Ogasawara N.,
RA Kikuchi H.;
RT "Genome sequencing and analysis of Aspergillus oryzae.";
RL Nature 438:1157-1161(2005).
CC -!- FUNCTION: Involved in cell fusion during mating by stabilizing the
CC plasma membrane fusion event. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane
CC protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the PRM1 family. {ECO:0000305}.
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DR EMBL; AP007155; BAE58195.1; -; Genomic_DNA.
DR RefSeq; XP_001820197.1; XM_001820145.1.
DR AlphaFoldDB; Q2UJS0; -.
DR STRING; 510516.Q2UJS0; -.
DR EnsemblFungi; BAE58195; BAE58195; AO090003001100.
DR GeneID; 5992180; -.
DR KEGG; aor:AO090003001100; -.
DR VEuPathDB; FungiDB:AO090003001100; -.
DR HOGENOM; CLU_010191_1_0_1; -.
DR OMA; QTYLCLF; -.
DR Proteomes; UP000006564; Chromosome 2.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0043332; C:mating projection tip; IEA:InterPro.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR026777; PRM1.
DR PANTHER; PTHR31030; PTHR31030; 1.
PE 3: Inferred from homology;
KW Cell membrane; Conjugation; Glycoprotein; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..722
FT /note="Plasma membrane fusion protein prm1"
FT /id="PRO_0000337271"
FT TOPO_DOM 1..54
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 55..75
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 76..122
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 123..143
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 144..320
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 321..341
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 342..406
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT TRANSMEM 407..427
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 428..609
FT /note="Extracellular"
FT /evidence="ECO:0000250"
FT TRANSMEM 610..630
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 631..722
FT /note="Cytoplasmic"
FT /evidence="ECO:0000250"
FT CARBOHYD 177
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 220
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 238
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 245
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 274
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 279
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 454
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 461
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 483
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 490
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 505
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 564
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
FT CARBOHYD 565
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 722 AA; 78583 MW; EEAC68113455828C CRC64;
MVFSRSGRSI FPLLPPYGAH DPNGGPGRAV PLHPDGITPY LGLRARLSQV WLNRWTILLL
LVLARVLIAA TGMQSDMDSA KREAQSACTS VETMGSAMAS MPHYLSRGVN ELTASGVEAA
VNGLISMLLL TITGVEALII FFIKVMYQTY LCLFTMVVRG STQAALGVIQ DTTEFLNKTV
QTVGEDIGKA VETFESGLNK FLSGINKVAS AFGGEVPTLN ISKNIDELKD IHLPGSINDT
IDKINSSIPT FDEVDKFVTD VLKFPFEEVK SLINGSLGNY TFDRSALPVP AKEQLTFCDE
NNGINTFFRK VAETIVAARK IFLAVLIIAA TLVCVPVAWQ EIRRWRTMKE RSQIVRKDAH
DPMDVVYIVS RPHTAGAGIK AASRFSNSRR QILVRWAIAY ATSPAALFVL CLALAGLFAC
LCQYLLLKAI ERTVPELTSE VGEFAEKVVT SLQNTSAKWA NDTNGVIDGM SNDINKNVLG
WVNTSTTAVN DTLNAFVDKT TGVLNDTFGG TILYSPLQDV FNCLIGLKVA SVQKGLTWVH
DHAHVDFPHV PNDILSKGAD SSINNSTSAS DSFLANPGDK TSDKITEVVM RVLNKIKEGV
RTETIISACV LGIWFINFLF GLIRAMILFW GRDKNRGEGG GAPINNNPDV NGFTEVPLTA
IPNTQAASLP APRYEVALKT PPVVGHFHED EKMGYAGQRA LKVDGTSDLR GSSYIEYGIE
KR
